Secher L, Weismann K, Kobayasi T
Acta Derm Venereol. 1982;62(5):407-11.
Biopsies for electron microscopy were obtained from syphilitic chancres of 7 patients, 6 males and one female. In 4 of the patients, Treponemata pallida were seen gathering around peripheral nerves and invading the spaces between Schwann cells and their basal lamina. No definite degenerative changes were seen in the axons. In all patients, Treponemata pallida were gathering around the small blood vessels. The fine structure of Treponema pallidum in the lesions included a twined cytoplasmic cylinder with an inner and an outer lamina, an axial fibril consisting of three to five parallel filaments, each consisting of six microtubules, and a covering, outpouching periplastic membrane.
对7例患者（6例男性，1例女性）的梅毒硬下疳进行了电子显微镜活检。在4例患者中，可见苍白螺旋体聚集在周围神经周围，并侵入施万细胞与其基膜之间的间隙。轴突未见明确的退行性改变。所有患者中，苍白螺旋体均聚集在小血管周围。病变中梅毒螺旋体的精细结构包括一个有内、外层膜的缠绕细胞质圆柱体、一个由三到五根平行细丝组成的轴丝，每根细丝由六个微管组成，以及一层覆盖的、向外突出的周质膜。
