Yu Cui, Longfei Liu, Long Wang, Feng Zeng, Jiping Niu, Mao Li, Lin Qi, Hequn Chen
Department of Urology, Xiangya Hospital, Central South University, Changsha, 410000, Hunan, China.
Int Urol Nephrol. 2014 Apr;46(4):719-25. doi: 10.1007/s11255-013-0588-7. Epub 2013 Oct 27.
Previous studies on the association between extracorporeal shock wave lithotripsy (SWL) and new onset hypertension have only illustrated contradictory results. In order to illustrate the association between SWL and new onset hypertension, a meta-analysis of case-control and cohort studies was conducted.
Relevant literature was searched using PubMed, EMBASE, and the Cochrane Central Search Library. A meta-analysis of the association between SWL and new onset hypertension was performed. Studies were pooled, and summary relative risk was calculated. Subgroup analyses were also conducted.
Eleven studies were eligible for our analysis. No statistical significance was detected between SWL and new onset hypertension (RR = 1.06, 95 % CI 0.83-1.35). No association was observed when stratified analyses were performed on age, gender, study design, bilateral SWL, and different machines.
Our analysis indicated that no association was found between SWL and the development of hypertension.
既往关于体外冲击波碎石术（SWL）与新发高血压之间关联的研究仅得出了相互矛盾的结果。为阐明SWL与新发高血压之间的关联，我们对病例对照研究和队列研究进行了荟萃分析。
通过检索PubMed、EMBASE和Cochrane中心对照试验注册库获取相关文献。对SWL与新发高血压之间的关联进行荟萃分析。汇总各项研究，并计算总结相对风险。同时进行亚组分析。
11项研究符合我们的分析标准。SWL与新发高血压之间未检测到统计学显著性差异（RR = 1.06，95%CI 0.83 - 1.35）。在按年龄、性别、研究设计、双侧SWL以及不同机器进行分层分析时，未观察到关联。
我们的分析表明，未发现SWL与高血压的发生之间存在关联。
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