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用于良性食管渗漏和穿孔的自膨式支架:单中心长期经验

Self-expandable stents for benign esophageal leakages and perforations: long-term single-center experience.

作者信息

Gubler Christoph, Bauerfeind Peter

机构信息

Clinic of Gastroenterology and Hepatology, University Hospital Zurich , Switzerland.

出版信息

Scand J Gastroenterol. 2014 Jan;49(1):23-9. doi: 10.3109/00365521.2013.850735. Epub 2013 Oct 28.

Abstract

OBJECTIVE

To date, there is no standardized treatment for esophageal perforations and leakages caused by underlying benign diseases, and it is still debated whether a conservative, endoscopic treatment or a surgical approach is preferable. However, some cases series have successfully demonstrated the feasibility of a temporary placement of self-expanding stents.

DESIGN

All patients with benign leakages of the esophagus or gastroesophageal junction or fistulas at gastroesophageal anastomosis were collected during the past 12 years and analyzed retrospectively. The patients treated with endoscopic stenting were analyzed for sustained success, complications, time to stenting, lesion size, number of stents used, need for percutaneous drainage.

RESULTS

Eighty-five of eight-eight patients were included in this analysis. Three patients were conservatively managed only. The success rate of stent treatment with an average of 1.3 stents was 79%. Success was highest (94%, n = 30 of 32, no complications or mortality) in iatrogenic lesions that were immediately diagnosed and treated. Spontaneous lesions, including lesions due to Boerhaave's syndrome, were healed in 73% and anastomotic leakages were closed in 71%. Fistula had a lower success rate of 43%. Use of multiple stents sequentially placed was necessary in 23% of the cases. Percutaneous drainage was necessary in 25% of all cases.

CONCLUSION

Temporary stent placement for benign leakages of the esophagus is safe and seems to improve treatment success. Adjacent fluid collections should be drained percutaneously.

摘要

目的

迄今为止,对于由潜在良性疾病引起的食管穿孔和渗漏尚无标准化治疗方法,保守治疗、内镜治疗或手术治疗哪种更可取仍存在争议。然而,一些病例系列已成功证明了临时放置自膨式支架的可行性。

设计

收集过去12年中所有食管或胃食管交界处良性渗漏或胃食管吻合口瘘的患者,并进行回顾性分析。对接受内镜支架置入治疗的患者分析其持续成功率、并发症、支架置入时间、病变大小、使用的支架数量、经皮引流的必要性。

结果

88例患者中有85例纳入本分析。3例患者仅接受保守治疗。平均使用1.3个支架的支架治疗成功率为79%。在立即诊断和治疗的医源性病变中成功率最高(94%,32例中的30例,无并发症或死亡)。自发性病变,包括由博赫哈夫综合征引起的病变,愈合率为73%,吻合口渗漏闭合率为71%。瘘的成功率较低,为43%。23%的病例需要依次放置多个支架。25%的病例需要经皮引流。

结论

临时放置支架治疗食管良性渗漏是安全的,似乎能提高治疗成功率。应经皮引流相邻的积液。

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