利用多金属氧酸盐作为光催化剂光降解与阿尔茨海默病相关的β-折叠淀粉样纤维。
Photodegradation of β-sheet amyloid fibrils associated with Alzheimer's disease by using polyoxometalates as photocatalysts.
机构信息
Laboratory of Chemical Biology, Division of Biological Inorganic Chemistry, State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Graduate School of the Chinese Academy of Sciences, Changchun, Jilin 130022, China.
出版信息
Chem Commun (Camb). 2013 Dec 18;49(97):11394-6. doi: 10.1039/c3cc46772d.
PMID:24165705
Abstract
Herein we report that POMs can not only inhibit Aβ aggregation but also photodegrade Aβ, especially the oligomers, showing enhanced inhibition effects.
摘要
在此，我们报告称，POMs 不仅可以抑制 Aβ 聚集，还可以光降解 Aβ，特别是寡聚物，表现出增强的抑制效果。
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