Kataria Sant Prakash, Batra Ashima, Singh Gajender, Kumar Sanjay, Sen Rajeev
Department of Pathology, Pt B.D. Sharma PGIMS, Rohtak, Haryana, India.
J Neurosci Rural Pract. 2013 Aug;4(Suppl 1):S95-7. doi: 10.4103/0976-3147.116426.
While the nasopharynx is most commonly regarded by the otolaryngologist as a primary site of neoplastic involvement, it is also an avenue of spread of base-of-the-skull tumors presenting as bulging nasopharyngeal masses. Chordoma is a relatively rare tumor of the skull base and sacrum thought to originate from embryonic remnants of the notochord. Chordomas arising from the skull base/clivus are typically locally aggressive with lytic bone destruction. The optimal treatment may be photon/proton radiotherapy alone or combined with a gross total resection, when feasible. We report a case of intracranial chordoma presenting as nasopharyngeal mass.
虽然耳鼻喉科医生通常认为鼻咽是肿瘤累及的主要部位,但它也是颅底肿瘤以鼻咽部肿块突出形式扩散的途径。脊索瘤是一种相对罕见的颅底和骶骨肿瘤,被认为起源于脊索的胚胎残余物。起源于颅底/斜坡的脊索瘤通常具有局部侵袭性,并伴有溶骨性骨质破坏。最佳治疗方法可能是单独进行光子/质子放疗,或在可行时与全切除联合使用。我们报告一例以鼻咽部肿块形式出现的颅内脊索瘤病例。