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表现为鼻咽部肿块的颅底脊索瘤。

Chordoma of skull base presenting as nasopharyngeal mass.

作者信息

Kataria Sant Prakash, Batra Ashima, Singh Gajender, Kumar Sanjay, Sen Rajeev

机构信息

Department of Pathology, Pt B.D. Sharma PGIMS, Rohtak, Haryana, India.

出版信息

J Neurosci Rural Pract. 2013 Aug;4(Suppl 1):S95-7. doi: 10.4103/0976-3147.116426.

Abstract

While the nasopharynx is most commonly regarded by the otolaryngologist as a primary site of neoplastic involvement, it is also an avenue of spread of base-of-the-skull tumors presenting as bulging nasopharyngeal masses. Chordoma is a relatively rare tumor of the skull base and sacrum thought to originate from embryonic remnants of the notochord. Chordomas arising from the skull base/clivus are typically locally aggressive with lytic bone destruction. The optimal treatment may be photon/proton radiotherapy alone or combined with a gross total resection, when feasible. We report a case of intracranial chordoma presenting as nasopharyngeal mass.

摘要

虽然耳鼻喉科医生通常认为鼻咽是肿瘤累及的主要部位,但它也是颅底肿瘤以鼻咽部肿块突出形式扩散的途径。脊索瘤是一种相对罕见的颅底和骶骨肿瘤,被认为起源于脊索的胚胎残余物。起源于颅底/斜坡的脊索瘤通常具有局部侵袭性,并伴有溶骨性骨质破坏。最佳治疗方法可能是单独进行光子/质子放疗,或在可行时与全切除联合使用。我们报告一例以鼻咽部肿块形式出现的颅内脊索瘤病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36fe/3808073/633aa2165ea1/JNRP-4-95-g001.jpg

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