Dwianingsih Ery Kus, Snak Yosinta, Rinonce Hanggoro Tri, Wasita Brian, Antoro Ester Lianawati, Amr Samir S
Department of Anatomical Pathology, Faculty of Medicine Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Department of Anatomical Pathology, Faculty of Medicine, Universitas Sebelas Maret, Solo, Indonesia.
Case Rep Pathol. 2019 Sep 23;2019:3826521. doi: 10.1155/2019/3826521. eCollection 2019.
Primary chordoma of the nasopharynx is an extremely rare malignant tumor of notochordal origin in the extra-osseous axial skeleton. It presents as a soft tissue mass without involvement of the skull base bone (clivus) and may mimic other lesions of the nasopharynx. A 26-year-old male patient is presented with nasal obstruction and congestion for the last 3 years. Physical and radiological examination revealed a mass in the naso-oropharyngeal region. It was suspected to be a cystic mass or abscess on radiological imaging. However, histopathological examination revealed a chordoma. We review all 20 cases of primary nasopharyngeal chordoma reported previously in the literature. Nasopharyngeal chordoma should be considered in the differential diagnosis of nasopharyngeal mass due to its unspecific appearance on clinical and radiology examination.
原发性鼻咽脊索瘤是一种极为罕见的起源于脊索的恶性肿瘤，位于骨外中轴骨骼。它表现为软组织肿块，不累及颅底骨（斜坡），可能酷似鼻咽部的其他病变。本文报道了一名26岁男性患者，在过去3年中出现鼻塞和鼻充血症状。体格检查和影像学检查发现鼻-口咽区域有一个肿块。影像学检查怀疑是囊性肿块或脓肿。然而，组织病理学检查显示为脊索瘤。我们回顾了文献中先前报道的所有20例原发性鼻咽脊索瘤病例。由于鼻咽脊索瘤在临床和影像学检查中表现不具特异性，因此在鼻咽部肿块的鉴别诊断中应考虑到该病。
