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药物信念在哮喘患者人格特质与依从行为之间作为中介变量的作用。

The function of medication beliefs as mediators between personality traits and adherence behavior in people with asthma.

作者信息

Axelsson Malin, Cliffordson Christina, Lundbäck Bo, Lötvall Jan

机构信息

Krefting Research Centre, Institute of Medicine, Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden ; Department of Nursing, Health and Culture, University West, Trollhättan, Sweden.

出版信息

Patient Prefer Adherence. 2013 Oct 22;7:1101-9. doi: 10.2147/PPA.S49725. eCollection 2013.

DOI:10.2147/PPA.S49725
PMID:24174872
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3808229/
Abstract

BACKGROUND

There is evidence that both personality traits and personal beliefs about medications affect adherence behavior. However, limited research exists on how personality and beliefs about asthma medication interact in influencing adherence behavior in people with asthma. To extend our knowledge in this area of adherence research, we aimed to determine the mediating effects of beliefs about asthma medication between personality traits and adherence behavior.

METHODS

Asthmatics (n=516) selected from a population-based study called West Sweden Asthma Study completed the Neuroticism, Extraversion and Openness to Experience Five-Factor Inventory, the Medication Adherence Report Scale, and the Beliefs about Medicines Questionnaire. Data were analyzed using confirmatory factor analysis and structural equation modeling.

RESULTS

Three of the five investigated personality traits - agreeableness, conscientiousness, and neuroticism - were associated with both concerns about asthma medication and adherence behavior. Concerns functioned as a partial mediator for the influencing effects of agreeableness, conscientiousness, and neuroticism on adherence behavior.

CONCLUSION

The findings suggest that personality traits could be used to identify individuals with asthma who need support with their adherence behavior. Additionally, targeting concerns about asthma medication in asthmatics with low levels of agreeableness or conscientiousness or high levels of neuroticism could have a favorable effect on their adherence behavior.

摘要

背景

有证据表明人格特质和对药物的个人信念都会影响依从行为。然而，关于人格与对哮喘药物的信念如何相互作用以影响哮喘患者的依从行为，相关研究有限。为了扩展我们在这一依从性研究领域的知识，我们旨在确定对哮喘药物的信念在人格特质与依从行为之间的中介作用。

方法

从一项名为瑞典西部哮喘研究的基于人群的研究中选取的哮喘患者（n = 516）完成了神经质、外向性和开放性经验五因素量表、药物依从性报告量表以及药物信念问卷。使用验证性因素分析和结构方程模型对数据进行分析。

结果

所调查的五种人格特质中的三种——宜人性、尽责性和神经质——均与对哮喘药物的担忧以及依从行为相关。担忧在宜人性、尽责性和神经质对依从行为的影响中起到部分中介作用。

结论

研究结果表明，人格特质可用于识别需要在依从行为方面获得支持的哮喘患者。此外，针对宜人性或尽责性水平较低或神经质水平较高的哮喘患者对哮喘药物的担忧进行干预，可能会对他们的依从行为产生积极影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c7/3808229/39c9b8ae4ea8/ppa-7-1101Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c7/3808229/e89d6b070f0f/ppa-7-1101Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c7/3808229/f96261a3dbab/ppa-7-1101Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c7/3808229/48ab97671cd0/ppa-7-1101Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c7/3808229/39c9b8ae4ea8/ppa-7-1101Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c7/3808229/e89d6b070f0f/ppa-7-1101Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c7/3808229/f96261a3dbab/ppa-7-1101Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c7/3808229/48ab97671cd0/ppa-7-1101Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c7/3808229/39c9b8ae4ea8/ppa-7-1101Fig4.jpg

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