Ferretti Fabio, Goracci Arianna, Laurenzi Pier Francesco, Centola Rossella, Crecchi Irene, De Luca Aldo, Monzillo Janette, Guidi Omar, Sinigaglia Giusy, Gualtieri Giacomo, Lorenzi Lore, Cuomo Alessandro, Bolognesi Simone, Travagli Valter, Coluccia Anna, Fagiolini Andrea, Pozza Andrea
Department of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.
Department of Molecular Medicine, School of Medicine, University of Siena, 53100 Siena, Italy.
Brain Sci. 2022 Sep 29;12(10):1315. doi: 10.3390/brainsci12101315.
After the declaration of the pandemic status in several countries, the continuity of face-to-face visits in psychiatric facilities has been delayed or even interrupted to reduce viral spread. Little is known about the personality factors associated with medication beliefs and adherence amongst individuals with mental illness during the COVID-19 pandemic. This brief report describes a preliminary naturalistic longitudinal study that explored whether the Big Five personality traits prospectively moderate the effects of medication beliefs on changes in adherence during the pandemic for a group of outpatients with psychosis or bipolar disorder.
Thirteen outpatients undergoing routine face-to-face follow-up assessments during the pandemic were included (41 observations overall) and completed the Revised Italian Version of the Ten-Item Personality Inventory, the Beliefs about Medicines Questionnaire, the Morisky Medication Adherence Scale-8-item and the Beck Depression Inventory-II.
Participants had stronger concerns about their psychiatric medications rather than beliefs about their necessity, and adherence to medications was generally low. Participants who had more necessity beliefs than concerns had better adherence to medications. People scoring higher in Conscientiousness and Neuroticism traits and more concerned about the medication side effects had poorer adherence.
These preliminary data suggest the importance of a careful assessment of the adherence to medications amongst people with psychosis/bipolar disorder during the pandemic. Interventions aimed to improve adherence might focus on patients' medication beliefs and their Conscientiousness and Neuroticism personality traits.
在多个国家宣布进入疫情状态后，精神科机构面对面就诊的连续性被推迟甚至中断，以减少病毒传播。关于新冠肺炎疫情期间与精神疾病患者用药信念和依从性相关的人格因素，人们了解甚少。本简要报告描述了一项初步的自然主义纵向研究，该研究探讨了在疫情期间，对于一组患有精神病或双相情感障碍的门诊患者，大五人格特质是否前瞻性地调节用药信念对依从性变化的影响。
纳入了13名在疫情期间接受常规面对面随访评估的门诊患者（共41次观察），他们完成了意大利语修订版的十项人格量表、用药信念问卷、8项版的莫里isky用药依从性量表以及贝克抑郁量表第二版。
参与者对精神科药物的担忧多于对其必要性的信念，并且用药依从性普遍较低。必要性信念多于担忧的参与者用药依从性更好。尽责性和神经质特质得分较高且更担心药物副作用的人依从性较差。
这些初步数据表明，在疫情期间仔细评估精神病/双相情感障碍患者的用药依从性非常重要。旨在提高依从性的干预措施可能侧重于患者的用药信念以及他们的尽责性和神经质人格特质。
