Artene Stefan-Alexandru, Ciurea Marius Eugen, Purcaru Stefana Oana, Tache Daniela Elise, Tataranu Ligia Gabriela, Lupu Mihaela, Dricu Anica
University of Medicine and Pharmacy of Craiova, Romania.
ScientificWorldJournal. 2013 Sep 23;2013:343275. doi: 10.1155/2013/343275. eCollection 2013.
Biobank is a very sophisticated system that consists of a programmed storage of biological material and corresponding data. Biobanks are created to be used in medical research, in clinical and translational medicine, and in healthcare. In the past 20 years, a large number of biobanks have been set up around the world, to support the modern research directions in medicine such as omix and personalized medicine. More recently, embryonic and adult stem cell banks have been developed. Stem cell banking was reported to be required for medical research as well as clinical transplant applications. The quality of the samples stored in a biobank is very important. The standardization is also important; the biological material stored in a biobank must be processed in a manner that allows compatibility with other biobanks that preserve samples in the same field. In this paper, we review some issues related to biobanks purposes, quality, harmonization, and their financial and ethical aspects.
生物样本库是一个非常复杂的系统,它由生物材料和相应数据的程序化存储组成。建立生物样本库是为了用于医学研究、临床和转化医学以及医疗保健领域。在过去20年里,世界各地建立了大量生物样本库,以支持诸如组学和个性化医学等现代医学研究方向。最近,胚胎干细胞库和成人干细胞库也得到了发展。据报道,干细胞库对于医学研究以及临床移植应用都是必需的。存储在生物样本库中的样本质量非常重要。标准化也很重要;存储在生物样本库中的生物材料必须以与同一领域中保存样本的其他生物样本库兼容的方式进行处理。在本文中,我们回顾了一些与生物样本库的目的、质量、协调以及其财务和伦理方面相关的问题。