Anatomy, University of Hong Kong, L1-59, Laboratory Block, 21 Sassoon Road, Hong Kong, Hong Kong.
BMC Med Ethics. 2013 Oct 31;14:43. doi: 10.1186/1472-6939-14-43.
With a view to addressing the moral concerns about the use of donor siblings, the Policy Statement of the American Academy of Pediatrics - Children as Hematopoietic Stem Cell Donors (the Policy) has laid out the criteria upon which tissue harvest from a minor would be permissible.
Although tissue harvest serves the best interests of recipient siblings, parents are also obliged to act in the best interests of the donor sibling in the UK. Tissue harvest should proceed if and only if it serves the best interests of both the donor and recipient. Parents should be forbidden, and they are by UK law, to consent to tissue harvest unless there are substantial benefits for an incompetent minor that can outweigh the potential harm. There is no basis to subject a minor to the medical risks of tissue harvest if the recipient sibling can wait without significant risks of complications until the donor becomes Gillick competent. We also argue that the Policy fails to take into account recent advances in haematopoietic transplantation from haploidentical donors or related tissue-matched donors.
Unless a recipient sibling will suffer from serious complications or die without the transplantation and no other medically equivalent donors are available, there is no moral or legal basis to violate the donor sibling's right to bodily integrity. Accordingly, we propose that the Policy should be modified in order to fully satisfy the legal requirements for application in the UK and other commonwealth jurisdictions with similar statute laws protecting minors.
为了解决使用供者兄弟姐妹所引发的道德问题,美国儿科学会的《造血干细胞供者儿童政策声明》(该政策)制定了从未成年人身上获取组织的可允许标准。
尽管组织采集符合受者兄弟姐妹的最佳利益,但在英国,父母也有义务为供者兄弟姐妹的最佳利益行事。只有当供者和受者都符合最佳利益时,才应该进行组织采集。除非对无行为能力的未成年人有实质性的好处,足以超过潜在的伤害,否则父母应被禁止(而且英国法律也是如此)同意进行组织采集。如果受者的兄弟姐妹可以等待,直到供者达到 Gillick 能力,而不会有重大并发症风险,那么就没有理由让未成年人承受组织采集的医疗风险。我们还认为,该政策没有考虑到来自半相合供者或相关组织匹配供者的造血移植的最新进展。
除非受者兄弟姐妹在没有移植的情况下会遭受严重并发症或死亡,并且没有其他医学等效的供者可用,否则没有道德或法律依据侵犯供者兄弟姐妹的身体完整性权利。因此,我们建议修改该政策,以便在英国和其他具有类似保护未成年人的成文法的英联邦司法管辖区完全满足适用的法律要求。