运动通过防止与年龄相关的早期灰质丢失来增加海马体体积。
Exercise boosts hippocampal volume by preventing early age-related gray matter loss.
机构信息
RG Animal models in Psychiatry, Department of Psychiatry and Psychotherapy, Central Institute of Mental Health Mannheim (ZI), Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
出版信息
Hippocampus. 2014 Feb;24(2):131-4. doi: 10.1002/hipo.22227. Epub 2013 Nov 26.
Recently, a larger hippocampus was found in exercising mice and men. Here we studied the morphological underpinnings in wheel running mice by longitudinal magnetic resonance imaging. Voxel-based morphometry revealed that running increases hippocampal volume by inhibiting an early age-related gray matter loss. Disruption of neurogenesis-related neuroplasticity by focalized irradiation is sufficient to block positive effects of exercise on macroscopic brain morphology.
最近，研究发现，经常运动的老鼠和人类的海马体更大。在此，我们通过纵向磁共振成像研究了滚轮运动老鼠的形态学基础。体素形态测量学显示，跑步通过抑制与年龄相关的早期灰质丢失来增加海马体的体积。通过聚焦辐射破坏与神经发生相关的神经可塑性足以阻止运动对大脑宏观形态的积极影响。
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