Ahmadi Afsane, Haghighat Neda, Hakimrabet Maryam, Tolide-ie Hamidreza
Department of Nutrition, School of Health and Nutrition, Shiraz University of Medical Sciences, Shiraz, Iran.
Pak J Biol Sci. 2012 May 15;15(10):501-5. doi: 10.3923/pjbs.2012.501.505.
Malnutrition is a common problem in moderate or severe Chronic Obstructive Pulmonary Disease (COPD) patients which affects body composition and food intake of these patients. In this study, the relationship of the stage of COPD with nutritional intake and body mass index in COPD patients were investigated and compared with healthy people and Dietary Reference Intake tables. A total of 93 COPD patients were referred by pulmonary physicians in Motahari and Faghihi medical centers. Pulmonary Function Test (PFT) was used in order to confirm the diagnosis of COPD and also categorize the patients into three categories (mild, moderate and sever). The control group consisted of 108 adults matched to the cases by age and gender. Anthropometric indices and physical activity and a 24 h dietary recall were recorded. All analyses were performed using the SPSS 14. All data presented as means (+/- SD). The mean intake of energy (p = 0.002), protein (p < 0.001), fat (p = 0.007), vitamin C (p = 0.003), vitamin E (p < 0.001), magnesium (p < 0.001) and omega-3 (p < 0.001) was significantly lower in COPD patients compared with controls. The mean BMI of the severe group was significantly lower than the controls (p = 0.016). The mean intake of energy, carbohydrate, fat, vitamin E, magnesium and omega-3 was significantly lower in both case and control groups compared to the RDA (p < 0.001) for all of the mentioned nutrients). Vitamin C intake was lower than RDA in the case (p < 0.001) and also in the control males (p < 0.001). In COPD patients, there is a significant relationship between the stage of COPD and nutrients intake and their BMI.
营养不良是中重度慢性阻塞性肺疾病(COPD)患者的常见问题,它会影响这些患者的身体组成和食物摄入。在本研究中,调查了COPD患者的疾病阶段与营养摄入及体重指数之间的关系,并与健康人群和膳食参考摄入量表进行比较。共有93例COPD患者由莫塔哈里和法吉希医疗中心的肺科医生转诊而来。使用肺功能测试(PFT)来确诊COPD,并将患者分为三类(轻度、中度和重度)。对照组由108名年龄和性别与病例匹配的成年人组成。记录人体测量指标、身体活动情况以及24小时饮食回顾。所有分析均使用SPSS 14进行。所有数据均以均值(±标准差)表示。与对照组相比,COPD患者的能量(p = 0.002)、蛋白质(p < 0.001)、脂肪(p = 0.007)、维生素C(p = 0.003)、维生素E(p < 0.001)、镁(p < 0.001)和ω-3(p < 0.001)的平均摄入量显著较低。重度组的平均BMI显著低于对照组(p = 0.016)。与所有上述营养素的推荐膳食摄入量(RDA)相比,病例组和对照组的能量、碳水化合物、脂肪、维生素E、镁和ω-3的平均摄入量均显著较低(p < 0.001)。病例组(p < 0.001)和对照组男性(p < 0.001)的维生素C摄入量均低于RDA。在COPD患者中,COPD疾病阶段与营养摄入及其BMI之间存在显著关系。