Hakeem Arsheed Hussain, Hazarika Biswajyoti, Hakeem Imtiyaz Hussain
Arsheed Hussain Hakeem, MD, Nesbit Road, Mazagaon,, Mumbai 400010, Maharashtra, India, T: +91-9920226332 F: (91-22) 25763344/3311,
Ann Saudi Med. 2013 Sep-Oct;33(5):492-4. doi: 10.5144/0256-4947.2013.492.
Clear cell myoepithelioma arising from the minor salivary glands of hard palate is a rare entity. Most of the cases of palatal myoepitheliomas reported so far are either plasmacytoid or spindle cell type. Our literature search revealed only one case report of clear cell myoepithelioma of the palate. We report a case in a 21-year-old female who presented to us with a non-ulcerating, painless firm swell.ing of the left side of the hard palate. The tumor was excised with a healthy rim of surrounding tissue. Immunohistochemistry was performed on formalin-fixed and paraffin-embedded tissue with a panel of immunohistochemical markers. Tumor cells showed positivity for S100, cytokeratin and Muscle specific actin. Histological and immunohistochemical analyses revealed the tumor to be a myoepithelioma of the clear cell variety.
起源于硬腭小唾液腺的透明细胞肌上皮瘤是一种罕见的疾病。迄今为止报道的大多数腭部肌上皮瘤病例为浆细胞样或梭形细胞型。我们的文献检索仅发现一例腭部透明细胞肌上皮瘤的病例报告。我们报告一例21岁女性病例,该患者因硬腭左侧出现非溃疡性、无痛性坚实肿物前来就诊。肿瘤连同周围健康组织边缘一并切除。对福尔马林固定、石蜡包埋的组织使用一组免疫组化标志物进行免疫组化检测。肿瘤细胞对S100、细胞角蛋白和肌肉特异性肌动蛋白呈阳性反应。组织学和免疫组化分析显示该肿瘤为透明细胞型肌上皮瘤。