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[为有HLA抗体的患者选择HLA配型相合的供者]

[Selection of HLA compatible donors for patients with HLA antibodies].

作者信息

Májský A, Korínková P, Kubícková Z

出版信息

Folia Haematol Int Mag Klin Morphol Blutforsch. 1985;112(6):937-43.

PMID:2419224
Abstract

A strain of 1,507 typised donors enables 15.97 average donors to be selected for a thrombocyte transfusion in one of 75 patients selected at random with HLA antibodies being previously determined (1 to 66 donors per patient). HLA compatible donors were found for 72 patients (97.33 per cent). More than 5 HLA compatible donors could be found for 58 patients. The high number of compatible donors is based on the fact that among 1,507 donors there were 156 HLA homozygotes and 556 donors with 3 HLA-A or B-antigens respectively. Compatibility in the ABO-system was not taken into account.

摘要

对1507名典型供者进行分型,在75名预先测定有HLA抗体的随机选择患者中(每名患者1至66名供者),进行血小板输注时平均可选择15.97名供者。为72名患者(97.33%)找到了HLA相容供者。58名患者能找到5名以上HLA相容供者。相容供者数量较多是基于以下事实:在1507名供者中,有156名HLA纯合子以及分别有556名具有3种HLA - A或B抗原的供者。未考虑ABO血型系统的相容性。

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