Department of Restorative Dentistry, College of Dentistry, Qassim University, Qassim, Saudi Arabia.
Photodiagnosis Photodyn Ther. 2013 Dec;10(4):632-43. doi: 10.1016/j.pdpdt.2013.07.006. Epub 2013 Aug 14.
The aim was to review the bactericidal efficacy of photodynamic therapy (PDT) against Enterococcus faecalis (E. faecalis) in infected root canals.
To address the focused question "Does PDT exhibit bactericidal effects against E. faecalis in infected root canals?" PubMed/Medline and Google-Scholar databases were searched from 1985 up to August 2013 using various combinations of the following key words: "antibacterial; "bactericidal; "endodontic; "root canal" and "photodynamic therapy". Original studies, experimental studies and articles published only in English language were included. Letters to the editor, historic reviews and unpublished data were excluded. The pattern of the present review was customized to primarily summarize the pertinent information.
Seventeen studies (16 ex vivo and one in vivo) were included. In these studies, numbers of teeth used ranged between 30 and 220 teeth. In these studies, wavelengths of diode laser used, diameter of fiber and power output ranged between 625 and 805 nm, 200 μm and 0.4 cm, and 40 mW and 5 W respectively. Twelve studies reported PDT to be effective in eliminating E. faecalis from infected root canals. Four studies reported conventional irrigation and instrumentation to be more efficient in killing E. faecalis than PDT. One study reported PDT and conventional endodontic regimes to be equally effective in eliminating E. faecalis from infected root canals. In most studies, toluidine blue and/or methylene blue were used as photosensitizers.
Efficacy of PDT in eliminating E. faecalis from infected root canals remains questionable.
评价光动力疗法（PDT）对粪肠球菌（E. faecalis）在感染根管中杀菌效果。
为了解决“PDT 对感染根管中的粪肠球菌是否具有杀菌作用？”这一具体问题，我们检索了 1985 年至 2013 年 8 月期间的 PubMed/Medline 和 Google-Scholar 数据库，使用了以下关键词的各种组合：“抗菌”、“杀菌”、“牙髓学”、“根管”和“光动力疗法”。纳入了原始研究、实验研究和仅以英语发表的文章。排除了给编辑的信、历史综述和未发表的数据。本综述的模式主要是总结相关信息。
纳入了 17 项研究（16 项离体研究和 1 项体内研究）。这些研究中使用的牙齿数量从 30 颗到 220 颗不等。在这些研究中，二极管激光的波长、光纤的直径和功率输出范围分别为 625nm 至 805nm、200μm 至 0.4cm 和 40mW 至 5W。12 项研究报告 PDT 能有效消除感染根管中的粪肠球菌。4 项研究报告传统冲洗和器械预备比 PDT 更能有效杀灭粪肠球菌。一项研究报告 PDT 和传统牙髓治疗方案在消除感染根管中的粪肠球菌方面同样有效。在大多数研究中，使用了甲苯胺蓝和/或亚甲蓝作为光敏剂。
PDT 消除感染根管中粪肠球菌的疗效仍存在疑问。
