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为增强美沙酮的效果而滥用加巴喷丁类药物:一项针对药物滥用者的调查。

Gabapentinoid abuse in order to potentiate the effect of methadone: a survey among substance misusers.

机构信息

University of Edinburgh, Edinburgh, UK.

出版信息

Eur Addict Res. 2014;20(3):115-8. doi: 10.1159/000355268. Epub 2013 Oct 31.

Abstract

BACKGROUND/AIMS: There is emerging evidence of gabapentin and pregabalin (gabapentinoid) abuse, particularly in the substance misuse population, and some suggestion of gabapentinoids being abused alongside methadone.

METHODS

A questionnaire-based survey was carried out in six substance misuse clinics, looking for evidence of gabapentinoid abuse.

RESULTS

22% (29/129) of respondents admitted to abusing gabapentinoids, and of these, 38% (11/29) abused gabapentinoids in order to potentiate the 'high' they obtained from methadone.

CONCLUSIONS

Gabapentinoid abuse along with methadone has not previously been described. These findings are of relevance to clinicians working within both substance misuse services and chronic pain services.

摘要

背景/目的:加巴喷丁和普瑞巴林(加巴喷丁类药物)的滥用现象日益明显,尤其是在物质滥用人群中,还有一些证据表明加巴喷丁类药物与美沙酮一起被滥用。

方法

在六家物质滥用诊所进行了一项基于问卷调查的调查,以寻找加巴喷丁类药物滥用的证据。

结果

22%(29/129)的受访者承认滥用加巴喷丁类药物,其中 38%(11/29)滥用加巴喷丁类药物是为了增强他们从美沙酮中获得的“快感”。

结论

加巴喷丁类药物与美沙酮一起滥用以前没有被描述过。这些发现与在物质滥用服务和慢性疼痛服务机构工作的临床医生有关。

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