Suppr超能文献

农药的相互作用:对报告的影响及其对野生动物风险评估的意义的综述。

Interactions between pesticides; a review of reported effects and their implications for wildlife risk assessment.

机构信息

Central Science Laboratory, MAFF, London Road, SL3 7HJ, Slough, Berkshire, UK.

出版信息

Ecotoxicology. 1996 Apr;5(2):59-81. doi: 10.1007/BF00119047.

Abstract

: Reviews of pesticide usage survey data and vertebrate wildlife and honeybee poisoning incident schemes in the UK show that there is considerable potential for wildlife to be exposed to combinations of agricultural pesticides. According to the published literature the toxicity of many pesticide combinations is at least additive. In some cases pesticide mixtures, particularly those involving insecticides, have been shown to be synergistic, with reported increases in toxicity of up to 100-fold. However, these effects are species, time and dose dependent and are therefore difficult to predict routinely. It is suggested that risk assessments should routinely take additive toxicity into account and those based on synergism should be targeted at those mixtures for which a further defined increase in toxicity would result in a high-risk classification. In order to support this risk assessment approach there is a need to develop and validate a standard in vivo test in order to confirm the interaction in those cases where additive or synergistic toxicity results in a high-risk classification.

摘要

: 对英国的农药使用调查数据和脊椎野生动物与蜜蜂中毒事件方案的审查表明,野生动物很有可能接触到农业农药的组合。根据已发表的文献,许多农药组合的毒性至少是相加的。在某些情况下,农药混合物,特别是涉及杀虫剂的混合物,已经被证明具有协同作用,毒性增加了高达 100 倍。然而,这些影响是物种、时间和剂量依赖性的,因此很难常规预测。有人建议,风险评估应常规考虑相加毒性,而基于协同作用的风险评估应针对那些混合物,如果毒性进一步明确增加,将导致高风险分类。为了支持这种风险评估方法,需要开发和验证一种标准的体内测试,以确认在那些相加或协同毒性导致高风险分类的情况下的相互作用。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验