Nentwich Martin M, Schebitz-Walter Kirsten, Hirneiss Christoph, Hintschich Christoph
Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany.
Orbit. 2014 Feb;33(1):33-8. doi: 10.3109/01676830.2013.844172. Epub 2013 Nov 6.
This study was performed to evaluate the outcome after autologous dermis-fat graft [DFG] orbital implants in a large sample.
A retrospective chart review of all primary and secondary DFGs in a 16-year period was done. Aesthetic and functional results, patients' satisfaction and postoperative complications were evaluated.
In total 468 DFGs were performed in the study period (315 primary [I°] and 153 secondary [II°] DGFs). In the analysis, 173 DFG I° and 66 DFG II° were included as sufficient follow-up was available. Median follow-up after DFG I° was 21.5 months and 14 months after DFG II°. After DFG I°, in 76% of patients motility of the graft was possible in all directions; 81% had good fitting of the prosthesis and 83% were highly satisfied with the results. Mean width of palpebral apertures was 0.2 mm smaller and Hertel exophthalmometry revealed a mean enophthalmus of 1.6 mm on the operated side compared to the fellow-eye. After DFG II°, motility was possible in all directions in 34% of patients. Fitting of the prosthesis was good/reasonable in 49%/41% and patients were highly satisfied in 57%. On average, on the operated side palpebral apertures were 0.6 mm smaller and Hertel measurements showed an enophthalmus of 2.6 mm. Major complications were uncommon. Complete necrosis of the implant was more often observed after II° (6.1%) than after I° DFG (3.5%).
In this large sample, DFG proved to be an effective and safe method for the reconstruction of anophthalmic sockets.
本研究旨在评估大样本自体真皮脂肪移植(DFG)眼眶植入术后的效果。
对16年间所有原发性和继发性DFG进行回顾性病历审查。评估美学和功能结果、患者满意度及术后并发症。
研究期间共进行了468例DFG(315例原发性[I°]和153例继发性[II°]DGF)。分析中纳入了173例I°DFG和66例II°DFG,因为有足够的随访数据。I°DFG后的中位随访时间为21.5个月,II°DFG后为14个月。I°DFG后,76%的患者移植体在各个方向均能活动;81%的患者假体贴合良好,83%的患者对结果高度满意。与健侧相比,患侧睑裂平均宽度小0.2mm,Hertel眼球突出计显示平均眼球内陷1.6mm。II°DFG后,34%的患者移植体在各个方向均能活动。49%/41%的患者假体贴合良好/尚可,57%的患者对结果高度满意。平均而言,患侧睑裂小0.6mm,Hertel测量显示眼球内陷2.6mm。主要并发症不常见。II°DFG(6.1%)后比I°DFG(3.5%)后更常观察到植入体完全坏死。
在这个大样本中,DFG被证明是一种有效且安全的无眼球眼眶重建方法。