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通过移除植入物和真皮脂肪移植治疗慢性无眼球眼窝疼痛。

Chronic anophthalmic socket pain treated by implant removal and dermis fat graft.

作者信息

Shams Pari N, Bohman Elin, Baker Meredith S, Maltry Amanda C, Kopp Eva Dafgård, Allen Richard C

机构信息

Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.

Division of Ophthalmology and Vision, Department of Clinical Neuroscience, Karolinska Institute, St. Erik Eye Hospital, Stockholm, Sweden.

出版信息

Br J Ophthalmol. 2015 Dec;99(12):1692-6. doi: 10.1136/bjophthalmol-2014-306585. Epub 2015 Jun 3.

Abstract

AIMS

To report the outcome of orbital implant removal and dermis fat graft (DFG) implantation in patients with chronic anophthalmic socket pain (ASP), in whom all detectable causes of pain had been ruled out and medical management had failed.

METHODS

Retrospective, multicentre case series. A review of all cases undergoing orbital implant replacement with DFG between 2007 and 2013 was conducted at the University of Iowa Hospitals and Clinics (UIHC), USA, and St. Erik Eye Hospital, Sweden. Inclusion criteria included (1) chronic ASP >2 years and unresponsive to treatment, (2) absence of pathological or structural cause for pain established by socket examination and orbital imaging, and (3) minimum 12-month post-surgical follow-up.

RESULTS

Six cases with chronic ASP were identified, four were post-enucleation and two were eviscerated at an average age of 45 years. The incidence of chronic ASP among enucleations at UIHC over a 6-year period was 0.7%. Indications for enucleation and evisceration included tumours and glaucoma. Intractable ASP had been present for an average of 11 years and persisted despite medical management. All patients were free of pain within 3 months of implant removal and DFG placement and remained pain free at an average 24 months following surgery.

CONCLUSIONS

Orbital implant replacement with DFG was effective at relieving chronic ASP, and pain resolution was sustained in all cases. This surgical intervention may be a useful management option for patients in whom all detectable causes of chronic pain have been excluded and have failed medical pain management.

摘要

目的

报告对慢性无眼球眼眶疼痛(ASP)患者进行眼眶植入物取出及真皮脂肪移植(DFG)植入的结果,这些患者已排除所有可检测到的疼痛原因且药物治疗无效。

方法

回顾性多中心病例系列研究。对2007年至2013年间在美国爱荷华大学医院及诊所(UIHC)和瑞典圣埃里克眼科医院接受DFG眼眶植入物置换的所有病例进行了回顾。纳入标准包括:(1)慢性ASP超过2年且对治疗无反应;(2)经眼眶检查和眼眶成像确定无疼痛的病理或结构原因;(3)术后至少随访12个月。

结果

确定了6例慢性ASP患者,4例为眼球摘除术后,2例为眼内容剜出术后,平均年龄45岁。UIHC在6年期间眼球摘除术中慢性ASP的发生率为0.7%。眼球摘除和眼内容剜出的指征包括肿瘤和青光眼。顽固性ASP平均存在11年,尽管进行了药物治疗仍持续存在。所有患者在植入物取出和DFG植入后3个月内均无疼痛,术后平均24个月仍无疼痛。

结论

用DFG进行眼眶植入物置换可有效缓解慢性ASP,且所有病例疼痛均持续缓解。对于已排除所有可检测到的慢性疼痛原因且药物止痛治疗无效的患者,这种手术干预可能是一种有用的治疗选择。

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