Department of Neurology, University of Bonn, Sigmund-Freud-Strasse 25, 53105, Bonn, Germany.
Cerebellum. 2014 Apr;13(2):237-42. doi: 10.1007/s12311-013-0532-5.
Whole body vibration (WBV) is a biomechanical treatment used widely in professional sports and rehabilitation. We examined the effect of stochastic WBV on ataxia in spinocerebellar ataxia types 1, 2, 3, and 6 (SCA 1, 2, 3 and 6) in a single-center double-blind sham-controlled study. Stochastic WBV was applied on four sequent days, each treatment consisting of five stimulus trains of 60-s duration at a frequency of 6.5 Hz and 60-s resting time between stimuli (n = 17). Patients allocated to the sham group received the same treatment with 1 Hz (n = 15). All patients were rated at baseline and after the last treatment using clinical scores (SARA, SCAFI, and INAS). After treatment, we found significant improvements of gait, posture, and speed of speech in the verum group while limb kinetics and ataxia of speech did not respond. Stochastic WBV might act on proprioceptive mechanisms and could also stimulate non-cerebellar/compensatory mechanisms. But at present, the involved cellular mechanism and the presumed neuronal loops cannot be deciphered. Thus, future work is needed to understand the mechanisms of whole body vibration. Finally, the use of stochastic WBV could provide a supplementation to treat ataxia in SCA and can be combined with physiotherapeutical motor training.
全身振动（WBV）是一种广泛应用于专业运动和康复的生物力学治疗方法。我们在一项单中心、双盲、假对照研究中，研究了随机 WBV 对脊髓小脑共济失调 1、2、3 和 6 型（SCA1、2、3 和 6）共济失调的影响。随机 WBV 连续 4 天应用，每次治疗由 60 秒频率为 6.5 Hz 的 5 个刺激列车和 60 秒刺激间隔组成（n=17）。假治疗组（n=15）接受相同的 1 Hz 治疗。所有患者在基线和最后一次治疗后使用临床评分（SARA、SCAFI 和 INAS）进行评分。治疗后，我们发现真实组的步态、姿势和言语速度有显著改善，而肢体动力学和言语共济失调没有反应。随机 WBV 可能作用于本体感觉机制，也可能刺激非小脑/代偿机制。但目前，涉及的细胞机制和假定的神经元回路尚无法破译。因此，需要进一步研究以了解全身振动的机制。最后，随机 WBV 的使用可以为 SCA 的共济失调治疗提供补充，并可以与物理治疗运动训练相结合。
