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为期3周的全身振动对轻度多发性硬化症患者的步态功能无改善作用——一项随机对照试验。

3-week whole body vibration does not improve gait function in mildly affected multiple sclerosis patients--a randomized controlled trial.

作者信息

Wolfsegger Thomas, Assar Hamid, Topakian Raffi

机构信息

Department of Neurology, Academic Teaching Hospital Wagner-Jauregg, Linz, Austria.

Department of Neurology, Academic Teaching Hospital Wagner-Jauregg, Linz, Austria.

出版信息

J Neurol Sci. 2014 Dec 15;347(1-2):119-23. doi: 10.1016/j.jns.2014.09.030. Epub 2014 Sep 26.

Abstract

OBJECTIVE

To investigate the effects of whole body vibration (WBV) training on gait function in persons with mild multiple sclerosis (MS).

DESIGN

A randomized controlled trial.

SUBJECTS

18 patients with MS were assigned randomly to WBV (intervention group) or to placebo WBV.

METHODS

Both groups performed a 3-week training period under static conditions on a vibration platform. In the placebo group, the vibration platform was covered and therefore vibrations could not operate. Gait function (gait velocity, stride length, double support phase, single-step variability left and right) was assessed at baseline, after 3-weeks of WBV intervention or sham WBV, 4-weeks after baseline, and 5-weeks after baseline using a mobile plantar food pressure system and the "Timed Up and Go" test under four different gait conditions (comfortable overground gait, comfortable gait on treadmill, -20% comfortable gait velocity on treadmill and +20% comfortable gait velocity on treadmill).

RESULTS

None of the outcome measures of gait function showed statistically significant alterations following 3-weeks of intervention/placebo WBV.

CONCLUSION

The applied protocol of WBV does not show a meaningful improvement of gait function in mildly affected MS patients.

摘要

目的

探讨全身振动(WBV)训练对轻度多发性硬化症(MS)患者步态功能的影响。

设计

一项随机对照试验。

研究对象

18例MS患者被随机分为WBV组(干预组)或安慰剂WBV组。

方法

两组均在振动平台上进行为期3周的静态训练。在安慰剂组中,振动平台被覆盖,因此无法产生振动。在基线时、WBV干预或假WBV干预3周后、基线后4周以及基线后5周,使用移动足底压力系统和“从坐到站”测试,在四种不同步态条件下(舒适的地面步态、跑步机上的舒适步态、跑步机上-20%舒适步态速度以及跑步机上+20%舒适步态速度)评估步态功能(步态速度、步长、双支撑期、左右单步变异性)。

结果

干预/安慰剂WBV 3周后,步态功能的各项指标均未显示出统计学上的显著变化。

结论

所应用的WBV方案并未显示出对轻度MS患者步态功能有有意义的改善。

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