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经颅磁刺激治疗痴呆症中药物难治性非妄想性幻听

Transcranial magnetic stimulation for the treatment of pharmacoresistant nondelusional auditory verbal hallucinations in dementia.

作者信息

Marras Anna, Pallanti Stefano

机构信息

University of Florence, 50137 Florence, Italy ; Institute of Neuroscience, 50121 Florence, Italy.

出版信息

Case Rep Psychiatry. 2013;2013:930304. doi: 10.1155/2013/930304. Epub 2013 Oct 2.

DOI:10.1155/2013/930304
PMID:24198993
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3808098/
Abstract

Auditory verbal hallucinations (AVHs) are known as a core symptom of schizophrenia, but also occur in a number of other conditions, not least in neurodegenerative disorders such as dementia. In the last decades, Transcranial Magnetic Stimulation (TMS) emerged as a valuable therapeutic approach towards several neurological and psychiatric diseases, including AVHs. Herein we report a case of a seventy-six-years-old woman with vascular-degenerative brain disease, complaining of threatening AVHs. The patient was treated with a high-frequency temporoparietal (T3P3) rTMS protocol for fifteen days. A considerable reduction of AVHs in frequency and content (no more threatening) was observed. Although further research is needed, this seems an encouraging result.

摘要

听幻觉(AVHs)是精神分裂症的核心症状,但也出现在许多其他病症中,尤其是在诸如痴呆症等神经退行性疾病中。在过去几十年中,经颅磁刺激(TMS)成为治疗包括听幻觉在内的多种神经和精神疾病的一种有价值的治疗方法。在此,我们报告一例患有血管退行性脑病的76岁女性病例,该患者主诉有威胁性听幻觉。患者接受了高频颞顶叶(T3P3)重复经颅磁刺激方案治疗15天。观察到听幻觉在频率和内容(不再具有威胁性)方面有显著减少。尽管还需要进一步研究,但这似乎是一个令人鼓舞的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3df4/3808098/6155c0566f5f/CRIM.PSYCHIATRY2013-930304.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3df4/3808098/6155c0566f5f/CRIM.PSYCHIATRY2013-930304.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3df4/3808098/6155c0566f5f/CRIM.PSYCHIATRY2013-930304.001.jpg

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Cognitive disconnective syndrome by single strategic strokes in vascular dementia.血管性痴呆中单策略性打击导致的认知断开综合征。
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