National Institute for Health and Welfare, Department of Mental Health and Substance Abuse Services, Helsinki, Finland.
Br J Psychiatry. 2010 Sep;197(3):200-6. doi: 10.1192/bjp.bp.109.070797.
Epidemiological data on alcohol-induced psychotic disorder and delirium (alcohol-induced psychotic syndrome, AIPS) are scarce.
To investigate the epidemiology of AIPS, the risk factors for developing AIPS among people with alcohol dependence, and mortality associated with alcohol dependence with or without AIPS, in a sample drawn from the general population of Finland.
A general population sample of 8028 persons were interviewed with the Composite International Diagnostic Interview and screened for psychotic disorders using multiple sources. Best-estimate diagnoses of psychotic disorders were made using the Structured Clinical Interview for DSM-IV Axis I Disorders and case notes. Data on hospital reatments and deaths were collected from national registers.
The lifetime prevalence was 0.5% for AIPS and was highest (1.8%) among men of working age. Younger age at onset of alcohol dependence, low socioeconomic status, father's mental health or alcohol problems and multiple hospital treatments were associated with increased risk of AIPS. Participants with a history of AIPS had considerable medical comorbidity, and 37% of them died during the 8-year follow-up.
Alcohol-induced psychotic disorder is a severe mental disorder with poor outcome.
关于酒精所致精神病性障碍和谵妄（酒精所致精神病综合征，AIPS）的流行病学数据很少。
在芬兰的一般人群样本中，调查 AIPS 的流行病学、酒精依赖患者发生 AIPS 的危险因素，以及酒精依赖伴或不伴 AIPS 的死亡率。
对 8028 名一般人群进行了访谈，采用复合国际诊断访谈进行了精神病学诊断，并通过多种来源进行了精神病筛查。使用 DSM-IV 轴 I 障碍的结构化临床访谈和病例记录对精神病学障碍进行了最佳估计诊断。从国家登记处收集了医院治疗和死亡数据。
AIPS 的终身患病率为 0.5%，在工作年龄的男性中患病率最高（1.8%）。酒精依赖发病年龄较早、社会经济地位较低、父亲的心理健康或酒精问题以及多次住院治疗与 AIPS 风险增加有关。有 AIPS 病史的参与者有相当多的合并症，在 8 年的随访中有 37%的人死亡。
酒精所致精神病性障碍是一种严重的精神障碍，预后不良。
