Xie Xiao-Yu, Wang Rui, Shi Yan-Ping
Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China.
Zhongguo Zhong Yao Za Zhi. 2013 Jul;38(14):2325-7.
Column chromatography on silica gel and Sephadex LH-20 was used to study the chemical constituents of Homalomena occulta. The chemical structures of the separated compounds were elucidated by spectroscopic data analyseS. Twelve compounds were obtained and identified as 5-pentylresorcinol-b-glucoside (1), protocatechuic acid (2), 4-hydroxybenzoic acid (3), vanillic acid (4), 5-hydroxymethyl-2-furancarboxylic acid (5), 2-furoic acid (6), 5-hydroxymethyl-2-furfural (7), (R) -malic acid (8), (R) -dimethyl malate (9), trimethyl 1,2,3-propanetricarboxylate (10), 4-hydroxytetrahydrofuran-2-one (11) and (1S, 2S, 4S)-p-menthane-1,2, 4-triol (12). Among them, compound 1 was a new natural product, and compounds 4-12 were isolated from the genus for the first time.
采用硅胶柱色谱和葡聚糖凝胶LH - 20柱色谱对千年健的化学成分进行了研究。通过光谱数据分析阐明了分离得到的化合物的化学结构。共得到12个化合物，分别鉴定为5 - 戊基间苯二酚 - β - 葡萄糖苷（1）、原儿茶酸（2）、4 - 羟基苯甲酸（3）、香草酸（4）、5 - 羟甲基 - 2 - 呋喃甲酸（5）、2 - 呋喃甲酸（6）、5 - 羟甲基 - 2 - 糠醛（7）、（R）-苹果酸（8）、（R）-苹果酸二甲酯（9）、1,2,3 - 丙三羧酸三甲酯（10）、4 - 羟基四氢呋喃 - 2 - 酮（11）和（1S, 2S, 4S）- 对薄荷烷 - 1,2, 4 - 三醇（12）。其中，化合物1为新天然产物，化合物4 - 12为首次从该属植物中分离得到。
