Bédane Ch
Service de Dermatologie, Hôpital Dupuytren, 2 avenue Martin Luther King 87042 Limoges, France.
Ann Dermatol Venereol. 2013 Nov;140 Suppl 2:229-35. doi: 10.1016/S0151-9638(13)70139-X.
PDT licensed indications in dermatology are actinic keratosis, Bowen's disease and superficial basal cell carcinomas. Skin tumors are sensitized by methyl aminomevulinate then illuminated with red light. Beyond these indication PDT is now widely used for the treatment of various others skin tumors and infectious or inflammatory skin disorders. PDT treatment of large areas can induce intense pain. Optimising PDT treatment needs to optimize pain control. Freezing or cooling procedure is the best way to decrease pain. The most interesting aspects of PDT is the absence of severe delayed adverse events and an optimal healing.
光动力疗法（PDT）在皮肤科的获批适应症为光化性角化病、鲍恩病和浅表基底细胞癌。皮肤肿瘤经甲基氨基酮戊酸致敏后，再用红光照射。除了这些适应症外，PDT现在还广泛用于治疗各种其他皮肤肿瘤以及感染性或炎症性皮肤病。大面积的PDT治疗会引发剧痛。优化PDT治疗需要优化疼痛控制。冷冻或冷却程序是减轻疼痛的最佳方法。PDT最吸引人的方面是没有严重的延迟性不良事件且愈合情况良好。
