Ben Zekry Sagit, Spiegelstein Dan, Sternik Leonid, Lev Innon, Kogan Alexander, Kuperstein Rafael, Raanani Ehud
Non-Invasive Cardiology Unit, Leviev Heart Center, Sheba Medical Center, Tel Hashomer, Israel; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Cardiac Surgery Department, Leviev Heart Center, Sheba Medical Center, Tel Hashomer, Israel; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
J Thorac Cardiovasc Surg. 2015 Nov;150(5):1071-7.e1. doi: 10.1016/j.jtcvs.2015.08.023. Epub 2015 Aug 13.
Mitral valve repair for myxomatous Barlow disease is a challenging procedure requiring complex surgery with less than optimal results. The use of ring-only repair has been previously reported but never analyzed or followed-up. We investigated this simple valve repair approach for patients with Barlow disease and multisegment involvement causing mainly central jet.
Of 572 patients who underwent mitral valve repair for mitral regurgitation at our medical center, 24 with Barlow disease (aged 47 ± 14 years; 46% male) underwent ring-only repair. Patients were characterized by severely enlarged mitral valve annulus, multisegment prolapse involving both leaflets, and demonstrated mainly a central wide regurgitant jet. Surgical technique included only the implantation of a large mitral annuloplasty ring. Early and late outcome results were compared with those of the remaining patients who underwent conventional mitral valve repair for degenerative disease (controls).
All ring-only patients presented with moderate-severe/severe mitral regurgitation (vena contracta, 0.6 ± 0.1 cm; regurgitation volume, 52 ± 17 mL), with mainly a central jet and almost preserved ejection fraction (59% ± 6%). Cardiopulmonary bypass and crossclamp times were significantly shorter compared with controls (P < .0001). At follow-up (ring-only, 38 ± 36 months and controls, 36 ± 29 months), there were no late deaths in the ring-only group compared with 19 (4%) in the controls. Late follow-up revealed New York Heart Association functional class I or II in 95% of ring-only patients, compared with 90% of controls. Freedom from recurrent moderate or severe mitral regurgitation was 100% and 89% in the ring-only and control groups, respectively.
Mitral annuloplasty for Barlow disease patients with multisegment involvement and mainly central regurgitant jet is both simple and reproducible with excellent late outcomes.
黏液瘤样巴洛病二尖瓣修复术是一项具有挑战性的手术,需要复杂的操作且效果不尽人意。此前有关于单纯使用瓣环修复的报道,但从未对其进行分析或随访。我们研究了这种针对巴洛病且多节段受累主要导致中央反流束的患者的简单瓣膜修复方法。
在我们医疗中心接受二尖瓣反流二尖瓣修复术的572例患者中,24例巴洛病患者(年龄47±14岁;46%为男性)接受了单纯瓣环修复。患者的特点是二尖瓣瓣环严重扩大、双叶多节段脱垂,且主要表现为中央宽反流束。手术技术仅包括植入一个大型二尖瓣成形环。将早期和晚期结果与其余接受退行性疾病传统二尖瓣修复术的患者(对照组)进行比较。
所有单纯瓣环修复患者均有中重度/重度二尖瓣反流(反流束颈宽,0.6±0.1cm;反流容积,52±17mL),主要为中央反流束,射血分数几乎保留(59%±6%)。与对照组相比,体外循环和主动脉阻断时间显著缩短(P<0.0001)。随访时(单纯瓣环修复组为38±36个月,对照组为36±29个月),单纯瓣环修复组无晚期死亡病例,而对照组有19例(4%)。晚期随访显示,95%的单纯瓣环修复患者纽约心脏协会心功能分级为Ⅰ或Ⅱ级,对照组为90%。单纯瓣环修复组和对照组无复发性中重度二尖瓣反流的比例分别为100%和89%。
对于多节段受累且主要为中央反流束的巴洛病患者,二尖瓣成形术操作简单且可重复,晚期效果良好。