González-Duarte Alejandra, Williams Ricardo
Departments of Neurology, Salvador Zubirán National Institute of Medical Sciences and Nutrition; Mexico City, Mexico -
Neuroradiol J. 2013 Oct;26(5):511-3. doi: 10.1177/197140091302600503. Epub 2013 Nov 7.
Cocaine-induced leukoencephalopathy is a rare neurological complication. It is most likely related to the substances used to adulterate the cocaine. Levamisole is one of the most common adulterants of cocaine and causes reversible leukoencephalopathy. Patients display severe neurological symptoms that resolve at termination of the exposure. MRI shows diffuse white matter involvement with sparing of the U fibers, without brain stem or cerebellar involvement. We describe the case of a woman with three neurologic episodes and remitting and recurrent brain white matter lesions.
可卡因所致白质脑病是一种罕见的神经系统并发症。它很可能与用于掺杂可卡因的物质有关。左旋咪唑是可卡因最常见的掺杂剂之一，可导致可逆性白质脑病。患者表现出严重的神经症状，在接触终止后症状会消失。磁共振成像显示弥漫性白质受累，U形纤维未受累，脑干和小脑未受累。我们描述了一名患有三次神经发作以及脑白质病变缓解和复发的女性病例。
