Department of Radiology, University Hospital of North Durham, County Durham and Darlington NHS Foundation Trust, Durham, UK.
Department of Radiology, Western Infirmary, Greater Glasgow and Clyde Hospitals NHS Trust, Glasgow, UK.
Clin Radiol. 2014 Feb;69(2):200-8. doi: 10.1016/j.crad.2013.09.011. Epub 2013 Nov 5.
Fibro-osseous lesions of the bone are well-recognized primary bone tumours. However, given the degree of overlap of imaging findings and variation in management of various sub-types, it is a widely accepted practice to perform a biopsy to obtain histopathological confirmation of the diagnosis. The following is a summary of the epidemiology, clinicopathological features, and review of the imaging features of fibro-osseous lesions, including osteofibrous dysplasia, osteofibrous dysplasia-like adamantinoma, adamantinoma, and lesions that closely mimic them. The illustrated examples are histologically proven cases that were presented to a tertiary referral teaching hospital and national bone and soft-tissue tumours unit. It is important that all radiologists are aware of the nature and imaging characteristics of these tumour sub-types, so that suspected lesions are recognized and appropriately referred to specialist bone tumour services for work-up and management.
骨的纤维-骨性病损是公认的原发性骨肿瘤。然而，鉴于影像学表现的重叠程度和各种亚型的治疗方法的差异，进行活检以获得病理诊断的组织学确证是一种广泛接受的做法。以下是纤维-骨性病损的流行病学、临床病理特征以及影像学特征的综述，包括纤维骨性发育不良、纤维骨性发育不良样造釉细胞瘤、造釉细胞瘤以及与其密切相似的病变。所举例证均为在三级转诊教学医院和国家骨与软组织肿瘤单位就诊并经组织学证实的病例。重要的是，所有放射科医生都应了解这些肿瘤亚型的性质和影像学特征，以便识别可疑病变，并将其适当转介至骨肿瘤专科，以进行进一步检查和管理。
