Doyle J A, Connolly S M, Hoagland H C
Acta Derm Venereol. 1985;65(6):521-5.
Review of 4 430 patients with a diagnosis of scleroderma, morphea, or eosinophilic fasciitis has revealed 16 patients with one of a variety of serious hematologic diseases. Although it is not possible to comment on the exact relationship between the dermatologic disease and the hematologic disorder, in seven patients there appeared to be a close temporal relationship between the onset of the two conditions. The development of a serious hematologic disease, especially a lymphoproliferative process, may rarely be seen not only in patients with eosinophilic fasciitis but also in those with systemic or localized scleroderma.
对4430例诊断为硬皮病、局限性硬皮病或嗜酸性筋膜炎的患者进行回顾后发现，有16例患者患有各种严重血液系统疾病中的一种。虽然无法评论皮肤病与血液系统疾病的确切关系，但在7例患者中，这两种疾病的发病在时间上似乎有密切关系。严重血液系统疾病的发生，尤其是淋巴增殖性病变，不仅在嗜酸性筋膜炎患者中很少见，在系统性或局限性硬皮病患者中也很少见。
