Wilson I H, Richmond M N, Strike P W
Br J Anaesth. 1986 Apr;58(4):401-5. doi: 10.1093/bja/58.4.401.
Sixty (ASA 1) patients were studied to determine the effect of bilateral local infiltration with 0.25% bupivacaine plain during third molar extraction under general anaesthesia. Bupivacaine infiltration significantly reduced the incidence of wide complex extrasystoles (P less than 0.05) during surgery and the severity of dental pain (P less than 0.05), when assessed at 6 h after operation.
对60名（ASA 1级）患者进行了研究，以确定在全身麻醉下拔除第三磨牙时，双侧局部浸润0.25%的单纯布比卡因的效果。在术后6小时评估时，布比卡因浸润显著降低了手术期间宽QRS波群早搏的发生率（P<0.05）以及牙痛的严重程度（P<0.05）。
