Munkhuu Bayalag, Essig Stefan, Renchinnyam Erdenesuvd, Schmid Raoul, Wilhelm Corina, Bohlius Julia, Chuluunbaatar Battulga, Shonkhuuz Enkhtur, Baumann Thomas
National Center for Maternal and Child Health, Ulaanbaatar, Mongolia.
PLoS One. 2013 Oct 24;8(10):e79427. doi: 10.1371/journal.pone.0079427. eCollection 2013.
In Mongolia, adequate early diagnosis and treatment of developmental hip dysplasia (DDH) have been unavailable and its incidence was unknown. We determined the incidence of ultrasonographic DDH in newborns and established adequate procedures for diagnosis and treatment of DDH at the largest maternity hospital in Ulaanbaatar, Mongolia.
METHODOLOGY/PRINCIPAL FINDINGS: During one year (Sept 2010 - Aug 2011) we assessed the hips newborns using ultrasound and Graf's classification of DDH. 8,356 newborns were screened; median age at screening was 1 day. We identified 14,873 Type 1 (89.0%), 1715 Type 2a (10.3%), 36 Type 2c (0.2%), 70 Type D (0.4%), 14 Type 3 (0.08%), and 4 Type 4 hips (0.02%). Children with Type 1 hips (normal) were discharged. Children with Type 2a hips (physiologically immature) received follow-up ultrasounds at monthly intervals. Children with Type 2c to 4 (DDH; deformed or misaligned hip joint) hips were treated with a Tubingen hip flexion splint and also followed up. The hip abnormalities resolved to mature hips in all children who were followed up. There was no evidence for severe treatment related complications.
CONCLUSION/SIGNIFICANCE: This study suggests that the incidence of DDH in Mongolian neonates is comparable to that in neonates in Europe. Early ultrasound-based assessment and splinting treatment of DDH led to mature hips in all children followed up. Procedures are feasible and will be continued.
在蒙古国,发育性髋关节发育不良(DDH)一直缺乏充分的早期诊断和治疗,其发病率也未知。我们在蒙古国乌兰巴托最大的妇产医院确定了新生儿超声诊断DDH的发病率,并建立了DDH诊断和治疗的适当程序。
方法/主要发现:在一年时间(2010年9月至2011年8月)内,我们使用超声和格拉夫DDH分类法对新生儿髋关节进行评估。共筛查了8356名新生儿;筛查时的中位年龄为1天。我们识别出14873例1型(89.0%)、1715例2a型(10.3%)、36例2c型(0.2%)、70例D型(0.4%)、14例3型(0.08%)和4例4型髋关节(0.02%)。1型髋关节(正常)的儿童出院。2a型髋关节(生理发育不成熟)的儿童每月接受一次超声随访。2c至4型(DDH;髋关节畸形或错位)髋关节的儿童采用图宾根髋关节屈曲夹板治疗并进行随访。所有接受随访的儿童髋关节异常均恢复为成熟髋关节。没有证据表明存在严重的治疗相关并发症。
结论/意义:本研究表明,蒙古新生儿DDH的发病率与欧洲新生儿相当。基于超声的DDH早期评估和夹板治疗使所有接受随访的儿童髋关节发育成熟。这些程序是可行的,并将继续进行。