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尿道狭窄女性患者行尿道成形术后生活质量得到改善。

Quality of life is improved after urethroplasty in women with urethral stricture.

作者信息

Tahra Ahmet, Sobay Resul, Küçük Eyüp Veli

机构信息

Department of Urology, Health Sciences University, Umraniye Training & Research Hospital, Istanbul, Turkey.

Department of Urology, Istanbul Medeniyet University, School of Medicine, Istanbul, Turkey.

出版信息

Int Urogynecol J. 2022 Mar;33(3):597-603. doi: 10.1007/s00192-021-05026-z. Epub 2022 Jan 9.

Abstract

INTRODUCTION AND HYPOTHESIS

To evaluate the quality of life (QoL) in women who underwent urethroplasty for urethral stricture.

METHODS

Twenty-two women who underwent ventral labium minus graft urethroplasty were included. Patients were assessed with uroflowmetry, urethral caliber and post-voiding residual urine (PVR). American Urological Association (AUA) symptom score, Urogenital Distress Inventory (UDI)-6 and Short Form-36 (SF-36) were used to evaluate QoL. Preoperative values were compared with patients' last visit data. The cure of the surgery was defined as a maximum flow rate > 15 ml/s in uroflowmetry and no need for any further intervention.

RESULTS

Median age was 55 (40-66) years. Cure was achieved in 20 (90.3%) patients with median 37 (13-52) months follow-up duration. The median Qmax increased from 4 (0-5) ml/s to 27.5 (8-55) ml/s (p < 0.001). Median post-void residual volume (PVR) decreased from 52.5 (0-120) ml to 20(0-60) ml (p = 0.011). Both AUA symptom score [from median 30 (24-35) to 4.5 (0-20), p < 0.001] and AUA-QoL score [from median 5 (4-6) to 0(0-3), p < 0.001] decreased after surgery. Median UDI summary score at the last follow-up was 0 (0-44.4), which was 33.3 (22.2-61.05) at baseline visit. Improvement was observed in all domains except the 'Energy/Fatigue' domain of the SF-36.

CONCLUSIONS

Urethroplasty is an effective surgical method to improve patients' QoL which is impaired because of female urethral stricture.

摘要

引言与假设

评估因尿道狭窄接受尿道成形术的女性的生活质量(QoL)。

方法

纳入22例行阴唇瓣移植尿道成形术的女性。对患者进行尿流率测定、尿道管径及排尿后残余尿量(PVR)评估。采用美国泌尿外科学会(AUA)症状评分、泌尿生殖系统困扰量表(UDI)-6和简明健康状况调查问卷(SF-36)评估生活质量。将术前值与患者最后一次随访数据进行比较。手术治愈定义为尿流率测定中最大尿流率>15 ml/s且无需进一步干预。

结果

中位年龄为55(40 - 66)岁。20例(90.3%)患者获得治愈,中位随访时间为37(13 - 52)个月。最大尿流率中位数从第4(0 - 5)ml/s增至27.5(8 - 55)ml/s(p < 0.001)。排尿后残余尿量中位数从52.5(0 - 120)ml降至20(0 - 60)ml(p = 0.011)。术后AUA症状评分[从中位数30(24 - 35)降至4.5(0 - 20),p < 0.001]和AUA生活质量评分[从中位数5(4 - 6)降至0(0 - 3),p < 0.001]均降低。最后一次随访时UDI总分中位数为0(0 - 44.4),基线访视时为33.3(22.2 - 61.05)。除SF-36的“精力/疲劳”领域外,所有领域均有改善。

结论

尿道成形术是改善因女性尿道狭窄而受损的患者生活质量的有效手术方法。

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