Keim V
Ann Nutr Metab. 1986;30(2):104-12. doi: 10.1159/000177182.
Pancreatic protein composition in basal and stimulated pancreatic juice was studied in conscious rats with cannulated pancreatic ducts. The animals were fed with 3 different diets for 14 days. Secretion rate was stimulated by acute derivation of the juice, intravenous infusion of cerulein and intraduodenal infusions of either amino acids, fat or carbohydrate. In the juice the amount of secretory proteins was measured. The various secretory stimuli did not lead to any rapid change of composition of the secreted enzymes. A so-called 'nonparallel secretion' of pancreatic enzymes could not be found in the conscious rat.
通过胰腺导管插管的清醒大鼠，研究基础状态和刺激状态下胰液中的胰腺蛋白质组成。给动物喂食3种不同的饮食14天。通过急性抽取胰液、静脉注射雨蛙素以及十二指肠内输注氨基酸、脂肪或碳水化合物来刺激分泌率。测定胰液中分泌蛋白的含量。各种分泌刺激并未导致分泌酶的组成发生任何快速变化。在清醒大鼠中未发现胰腺酶的所谓“非平行分泌”。
