就读于特殊需求教育/融合教育学校的学生的染色体异常。
Chromosome abnormalities in pupils attending ESN/M schools.
作者信息
Lamont M A, Dennis N R, Seabright M
出版信息
Arch Dis Child. 1986 Mar;61(3):223-6. doi: 10.1136/adc.61.3.223.
Abstract
One hundred and sixty six children attending educationally subnormal/mild (ESN/M) schools were karyotyped as part of a project investigating the aetiology of mild mental retardation. Nine had significant chromosome abnormalities. Five of six children identified during the survey had no dysmorphic features--47,XXY (two), 48,XXYY, 46,XX 15q-, and 46,XX,t(X;19). One dysmorphic boy had a balanced translocation--46,XY,t(3;15). Three were already known--47,XX+21 (two) and 46,XY, 14q+. We suggest that routine karyotyping of children with mild mental retardation be considered.
摘要
作为一项调查轻度智力迟钝病因的项目的一部分，对166名就读于教育程度低于正常水平/轻度（ESN/M）学校的儿童进行了核型分析。其中9名儿童有明显的染色体异常。在调查中确定的6名儿童中有5名没有畸形特征——47,XXY（2例）、48,XXYY、46,XX 15q-和46,XX,t(X;19)。一名畸形男孩有平衡易位——46,XY,t(3;15)。另外3例是已知的——47,XX+21（2例）和46,XY,14q+。我们建议考虑对轻度智力迟钝儿童进行常规核型分析。
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