Department of Obstetrics and Gynecology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan.
Fetal Diagn Ther. 2014;35(2):148-50. doi: 10.1159/000355601. Epub 2013 Nov 9.
Umbilical artery thrombosis (UAT) is rare and few prenatally diagnosed cases have been reported. We describe 2 cases of fetal growth restriction prenatally diagnosed as UAT by ultrasound examination. In each case the cross section of the umbilical cord showed one normal artery and a small echogenic area which was suspected as an occluded thrombotic artery and they were surrounded by a highly curving 'C-shaped' vein. UAT was confirmed by histological examinations after deliveries in both cases. The characteristic ultrasound finding of the umbilical vessel, which is the so-called 'orange grabbed sign', enables the prenatal diagnosis of UAT and it is valuable with respect to perinatal fetal management because UAT is associated with increased perinatal morbidity and mortality.
脐动脉血栓形成（UAT）较为罕见，且产前诊断的病例报道较少。我们描述了 2 例胎儿生长受限病例，通过超声检查产前诊断为 UAT。在每个病例中，脐带的横切面显示一条正常动脉和一个小的高回声区域，疑似为闭塞性血栓形成动脉，它们被一个高度弯曲的“C 形”静脉环绕。在这 2 例病例中，分娩后通过组织学检查证实了 UAT。脐血管的特征性超声表现，即所谓的“橙子抓痕征”，可实现 UAT 的产前诊断，这对于围产期胎儿管理具有重要价值，因为 UAT 与围产期发病率和死亡率增加有关。
