• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

组织学评估研究牙银合金和复合树脂修复对人牙髓的影响:一项体内研究。

Histological evaluation to study the effects of dental amalgam and composite restoration on human dental pulp: an in vivo study.

机构信息

Conservative Dentistry and Endodontics, Government Dental College and Hospital, Mumbai, India.

出版信息

Med Princ Pract. 2014;23(1):40-4. doi: 10.1159/000355607. Epub 2013 Nov 9.

DOI:10.1159/000355607
PMID:24217468
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5586846/
Abstract

OBJECTIVE

To study and compare the effects of dental amalgam and composite restorations on human dental pulp.

MATERIALS AND METHODS

One hundred sound premolars scheduled for orthodontic extraction were divided equally into two groups: group A, teeth restored with silver amalgam, and group B, teeth restored with composite resin. Each group was equally subdivided into two subgroups [extracted after 24 h (A-1 and B-1) or 7 days (A-2 and B-2)], and the histological changes in the pulp related to the two different materials at the two different intervals were studied.

RESULTS

It was found that after 24 h, the inflammatory response of the pulp in teeth restored with amalgam and composite was similar (p = 1.00). However, after 7 days, the severity of the inflammatory response of the pulp in teeth restored with amalgam was less compared to that in teeth restored with composite (p = 0.045).

CONCLUSION

This study confirmed that amalgam continues to be the mechanically as well as biologically more competent restorative material. Composite could be a promising restorative material to satisfy esthetic needs for a considerable period of time. However, its biological acceptance is still in doubt.

摘要

目的

研究和比较汞合金和复合树脂修复对人牙髓的影响。

材料与方法

100 颗正畸拔除的健康前磨牙均分为两组:A 组,用银汞合金修复;B 组,用复合树脂修复。每组又均分为 2 个亚组[分别在 24 小时(A-1 和 B-1)或 7 天后(A-2 和 B-2)拔出],研究两种不同材料在两个不同时间段对牙髓的组织学变化。

结果

发现,24 小时后,用汞合金和复合树脂修复的牙齿的牙髓炎症反应相似(p = 1.00)。然而,7 天后,用汞合金修复的牙齿的牙髓炎症反应的严重程度低于用复合树脂修复的牙齿(p = 0.045)。

结论

本研究证实,汞合金仍然是机械和生物学性能更优越的修复材料。复合树脂在相当长的一段时间内可能是一种有前途的满足美观需求的修复材料。但其生物相容性仍存在疑问。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3a8/5586846/af224df6c2ef/mpp-0023-0040-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3a8/5586846/b99b2c790131/mpp-0023-0040-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3a8/5586846/9dbdb723a94c/mpp-0023-0040-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3a8/5586846/c788f148814d/mpp-0023-0040-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3a8/5586846/7e2cd206aed6/mpp-0023-0040-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3a8/5586846/af224df6c2ef/mpp-0023-0040-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3a8/5586846/b99b2c790131/mpp-0023-0040-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3a8/5586846/9dbdb723a94c/mpp-0023-0040-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3a8/5586846/c788f148814d/mpp-0023-0040-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3a8/5586846/7e2cd206aed6/mpp-0023-0040-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3a8/5586846/af224df6c2ef/mpp-0023-0040-g05.jpg

相似文献

1
Histological evaluation to study the effects of dental amalgam and composite restoration on human dental pulp: an in vivo study.组织学评估研究牙银合金和复合树脂修复对人牙髓的影响:一项体内研究。
Med Princ Pract. 2014;23(1):40-4. doi: 10.1159/000355607. Epub 2013 Nov 9.
2
Direct composite resin fillings versus amalgam fillings for permanent or adult posterior teeth.恒牙或成人后牙的直接复合树脂补牙与汞合金补牙对比
Cochrane Database Syst Rev. 2014 Mar 31(3):CD005620. doi: 10.1002/14651858.CD005620.pub2.
3
Endodontic complications after plastic restorations in general practice.全科医疗中塑料修复后的牙髓并发症。
Int Endod J. 2005 Jun;38(6):409-16. doi: 10.1111/j.1365-2591.2005.00962.x.
4
Twelve-year survival of 2-surface composite resin and amalgam premolar restorations placed by dental students.牙科学生放置的双表面复合树脂和银汞合金前磨牙修复体的12年生存率。
J Prosthet Dent. 2016 Sep;116(3):336-9. doi: 10.1016/j.prosdent.2016.02.005. Epub 2016 Apr 14.
5
Fracture resistance of endodontically treated teeth restored with combined composite-amalgam restorations.采用复合树脂与汞合金联合修复的根管治疗后牙齿的抗折性。
Quintessence Int. 2008 Feb;39(2):e58-62.
6
Prevalence of cusp fractures in teeth restored with amalgam and with resin-based composite.用汞合金和树脂基复合材料修复的牙齿中尖折的患病率。
J Am Dent Assoc. 2004 Aug;135(8):1127-32; quiz 1164-5. doi: 10.14219/jada.archive.2004.0371.
7
Periapical status of non-root-filled teeth with resin composite, amalgam, or full crown restorations: a cross-sectional study of a Swedish adult population.采用树脂复合材料、汞合金或全冠修复的未进行根管充填牙齿的根尖周状况:一项针对瑞典成年人群的横断面研究
J Endod. 2014 Sep;40(9):1303-8. doi: 10.1016/j.joen.2014.05.002. Epub 2014 Jul 16.
8
[Amalgam. VIII. Substitute for amalgam: the biocompatibility of composite restorations].
Ned Tijdschr Tandheelkd. 1993 Sep;100(9):389-91.
9
Fracture strength of restored premolars.修复前磨牙的断裂强度。
Am J Dent. 2007 Apr;20(2):121-4.
10
[Dental filling material biocompatibility--is Amalgam the worst in supply?].
Rev Med Suisse. 2012 Jan 25;8(325):195-6.

引用本文的文献

1
Mechanically Induced Pulpitis: A Rat Model That Preserves Animal Well-Being.机械性诱导牙髓炎:一种保障动物健康的大鼠模型。
Biomedicines. 2025 Aug 7;13(8):1925. doi: 10.3390/biomedicines13081925.
2
Evaluation of pulpal response at varying remaining dentin thickness in teeth restored with resin bulk fill composite, conventional glass ionomer cement and silver amalgam: Histomorphometric analysis.树脂大块充填复合树脂、传统玻璃离子水门汀和银汞合金修复牙齿时不同剩余牙本质厚度下牙髓反应的评估:组织形态计量学分析
J Oral Biol Craniofac Res. 2025 Mar-Apr;15(2):347-354. doi: 10.1016/j.jobcr.2024.12.020. Epub 2025 Feb 12.
3
Influence of TEGDMA monomer on MMP-2, MMP-8, and MMP-9 production and collagenase activity in pulp cells.

本文引用的文献

1
Biocompatibility of dental amalgams.牙科汞合金的生物相容性。
Int J Dent. 2011;2011:981595. doi: 10.1155/2011/981595. Epub 2011 Nov 23.
2
Effect of different placement techniques on marginal microleakage of deep class-II cavities restored with two composite resin formulations.不同充填技术对两种复合树脂修复深II类洞边缘微渗漏的影响。
J Conserv Dent. 2010 Jan;13(1):9-15. doi: 10.4103/0972-0707.62633.
3
Experimental Investigation into the Early Effects of Various Filling Materials on the Human Pulp: (Section of Odontology).
三乙二醇二甲基丙烯酸酯单体对牙髓细胞 MMP-2、MMP-8 和 MMP-9 产生及胶原酶活性的影响。
Clin Oral Investig. 2021 Apr;25(4):2269-2279. doi: 10.1007/s00784-020-03545-5. Epub 2020 Aug 26.
4
Modifying Adhesive Materials to Improve the Longevity of Resinous Restorations.改性黏接材料以提高树脂修复体的寿命。
Int J Mol Sci. 2019 Feb 8;20(3):723. doi: 10.3390/ijms20030723.
5
Effect of various light curing times on the elution of composite components.不同光固化时间对复合树脂成分洗脱的影响。
Clin Oral Investig. 2016 Nov;20(8):2113-2121. doi: 10.1007/s00784-015-1698-7. Epub 2015 Dec 28.
6
Balancing the risks and benefits associated with cosmetic dentistry - a joint statement by UK specialist dental societies.平衡美容牙科的风险与益处——英国专业牙科协会联合声明
Br Dent J. 2015 May 8;218(9):543-8. doi: 10.1038/sj.bdj.2015.345.
不同充填材料对人牙髓早期影响的实验研究:(牙科学部分)
Proc R Soc Med. 1941 Sep;34(11):693-706. doi: 10.1177/003591574103401103.
4
Remaining challenges with Class II resin-based composite restorations.
J Am Dent Assoc. 2007 Nov;138(11):1487-9. doi: 10.14219/jada.archive.2007.0085.
5
Comparison of human pulp response to total-etch and self-etch bonding agents.人类牙髓对全酸蚀和自酸蚀粘结剂反应的比较。
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Aug;104(2):e45-52. doi: 10.1016/j.tripleo.2007.02.005. Epub 2007 Jun 7.
6
Adhesive resin induces apoptosis and cell-cycle arrest of pulp cells.黏附性树脂可诱导牙髓细胞凋亡并使其细胞周期停滞。
J Dent Res. 2003 Aug;82(8):592-6. doi: 10.1177/154405910308200804.
7
Comparison of pulp responses to resin composites.牙髓对树脂复合材料反应的比较。
Oper Dent. 2003 May-Jun;28(3):242-50.
8
An alternative method to reduce polymerization shrinkage in direct posterior composite restorations.一种减少直接后牙复合树脂修复体聚合收缩的替代方法。
J Am Dent Assoc. 2002 Oct;133(10):1387-98. doi: 10.14219/jada.archive.2002.0055.
9
Response of human pulps following acid conditioning and application of a bonding agent in deep cavities.深龋洞经酸处理及应用粘结剂后人牙髓的反应
Dent Mater. 2002 Nov;18(7):543-51. doi: 10.1016/s0109-5641(01)00089-6.
10
Bacterial microleakage and pulp inflammation associated with various restorative materials.与各种修复材料相关的细菌微渗漏和牙髓炎症。
Dent Mater. 2002 Sep;18(6):470-8. doi: 10.1016/s0109-5641(01)00072-0.