State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China.
Department of Cariology and Endodontics, West China School of Stomatology, Sichuan University, Chengdu 610041, China.
Int J Mol Sci. 2019 Feb 8;20(3):723. doi: 10.3390/ijms20030723.
Dental caries is a common disease on a global scale. Resin composites are the most popular materials to restore caries by bonding to tooth tissues via adhesives. However, multiple factors, such as microleakage and recurrent caries, impair the durability of resinous restorations. Various innovative methods have been applied to develop adhesives with particular functions to tackle these problems, such as incorporating matrix metalloproteinase inhibitors, antibacterial or remineralizing agents into bonding systems, as well as improving the mechanical/chemical properties of adhesives, even combining these methods. This review will sum up the latest achievements in this field.
龋齿是一种全球性的常见疾病。树脂复合材料通过黏结剂与牙体组织黏结，是最常用的龋损修复材料。然而，微渗漏和继发龋等多种因素影响了树脂修复体的耐久性。为了解决这些问题，人们已经应用了各种创新方法来开发具有特殊功能的黏结剂，例如将基质金属蛋白酶抑制剂、抗菌或再矿化剂纳入黏结体系，以及改善黏结剂的机械/化学性能，甚至结合这些方法。本文将总结该领域的最新研究进展。
