Agarwal Ankita, Verma Promila, Yadav Rakesh, Bharti Ramesh, Bains Rhythm, Kumar Madhu, Shastri Dipti
Department of Conservative Dentistry and Endodontics, Faculty of Dental Sciences, King George's Medical University, Lucknow, India.
Department of Pathology, King George's Medical University, Lucknow, India.
J Oral Biol Craniofac Res. 2025 Mar-Apr;15(2):347-354. doi: 10.1016/j.jobcr.2024.12.020. Epub 2025 Feb 12.
To compare and evaluate the pulp response to GC glass ionomer cement, SDR plus bulk fill composite and amalgam against gold standard calcium hydroxide cement at varying remaining dentin thickness, in teeth planned for orthodontic extraction.
Thirty-eight human premolars were prepared with 2 mm or 2.5 mm depth cavities. They were restored with GC conventional glass ionomer cement, SDR plus bulk fill composite, amalgam, or lined with Dycal and restored with GIC. Two teeth were used as intact controls. After a 7-day interval, the teeth were extracted and processed for histological examination of the pulp and the thickness of the remaining dentin between the cavity floor and pulp tissue.
All experimental groups showed some degree of inflammatory response. A significantly higher inflammatory response and more tissue disorganization were observed with SDR bulk fill composite (p < 0.05) compared to Glass ionomer cement, amalgam and Dycal at both cavity depths of 2 mm or 2.5 mm. The mean RDTs ranged from 346 μm to 1025 μm.
The study concluded that critical RDT varies for different restorative materials. It was observed that both glass ionomer cement and amalgam demonstrated acceptable biocompatibility when used in deep cavities. At the same time, SDR plus bulk fill composite proved to be the least biocompatible.
在计划进行正畸拔除的牙齿中,比较并评估在不同剩余牙本质厚度下,GC玻璃离子水门汀、SDR加体填充复合材料和汞合金相对于金标准氢氧化钙水门汀的牙髓反应。
将38颗人类前磨牙制备成深度为2毫米或2.5毫米的窝洞。分别用GC传统玻璃离子水门汀、SDR加体填充复合材料、汞合金进行修复,或先用Dycal垫底再用玻璃离子水门汀修复。将两颗牙齿作为完整对照。间隔7天后,拔除牙齿并进行处理,以对牙髓进行组织学检查,并测量窝洞底部与牙髓组织之间剩余牙本质的厚度。
所有实验组均表现出一定程度的炎症反应。在窝洞深度为2毫米或2.5毫米时,与玻璃离子水门汀、汞合金和Dycal相比,SDR体填充复合材料观察到明显更高的炎症反应和更多的组织紊乱(p<0.05)。平均剩余牙本质厚度范围为346微米至1025微米。
该研究得出结论,不同修复材料的临界剩余牙本质厚度不同。观察到玻璃离子水门汀和汞合金在用于深窝洞时均表现出可接受的生物相容性。同时,SDR加体填充复合材料被证明生物相容性最差。