Rakic Vesna S, Brasanac Dimitrije C, Janjić Zlata M, Bogdanovic Slobodan M, Arafeh Mazen A
From the *Clinic for Burns, Plastic and Reconstructive Surgery, Clinical Center of Serbia, Belgrade; †Institute of Pathology, School of Medicine, University of Belgrade, Belgrade; and ‡Clinic for Plastic and Reconstructive Surgery, Clinical Center of Vojvodina, Novi Sad, Serbia.
J Craniofac Surg. 2013 Nov;24(6):e610-4. doi: 10.1097/SCS.0b013e3182a2b744.
The giant, invasive basal cell carcinoma of the scalp is a rare clinical form of this tumor that appears on the skin, but may spread to some of the following structures: soft tissues of the scalp, bones, meninges, and the brain. In literature, so far, it is known as the GBCC. It is caused by aggressive BCC subtypes.
We will present here a research of clinical and pathological features of 47 pathological specimens in 31 patients where the following features were examined: the dimension of the tumor, the dimension of the tissue segment, tumor area, segmentation area, resection margin width, microscopic resection margin status, tumor invasion level, and the outcome.
We have concluded that microscopic resection margin dimensions from 1 to 10 mm are safe and that relapse occurrences in giant, invasive BCCs of the scalp depend on microscopic resection margin dimensions, resection margin status, tumor invasion levels, risky occupation, and risky behavior of the patient.
头皮巨大侵袭性基底细胞癌是该肿瘤一种罕见的临床类型，出现在皮肤上，但可能扩散至以下一些结构：头皮软组织、骨骼、脑膜和脑。在文献中，到目前为止，它被称为GBCC。它由侵袭性基底细胞癌亚型引起。
我们在此将展示对31例患者47个病理标本的临床和病理特征的研究，其中检查了以下特征：肿瘤大小、组织切片大小、肿瘤面积、切片面积、切除边缘宽度、显微镜下切除边缘状态、肿瘤侵袭水平及结果。
我们得出结论，1至10毫米的显微镜下切除边缘尺寸是安全的，头皮巨大侵袭性基底细胞癌的复发取决于显微镜下切除边缘尺寸、切除边缘状态、肿瘤侵袭水平、患者的高危职业和高危行为。
