Department of Animal Biotechnology, UBITA Center for Biotechnology Research (CBRU), Konkuk University, Seoul 143-701, Korea, Department of Bioengineering and Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Bioinformatics. 2014 Apr 1;30(7):1010-2. doi: 10.1093/bioinformatics/btt636. Epub 2013 Nov 12.
We developed PSAR-Align, a multiple sequence realignment tool that can refine a given multiple sequence alignment based on suboptimal alignments generated by probabilistic sampling. Our evaluation demonstrated that PSAR-Align is able to improve the results from various multiple sequence alignment tools.
The PSAR-Align source code (implemented mainly in C++) is freely available for download at http://bioen-compbio.bioen.illinois.edu/PSAR-Align.
我们开发了 PSAR-Align,这是一种多重序列比对工具,可以根据概率抽样生成的次优比对来优化给定的多重序列比对。我们的评估表明,PSAR-Align 能够改进各种多重序列比对工具的结果。
PSAR-Align 的源代码(主要用 C++实现)可在 http://bioen-compbio.bioen.illinois.edu/PSAR-Align 免费下载。