Mehring Michael, Donnachie Ewan, Fexer Johannes, Hofmann Frank, Schneider Antonius
Institute of General Practice, Technische Universität München, Munich, Germany.
National Association of Statutory Health Insurance Physicians of Bavaria, Munich, Germany.
Respir Care. 2014 Jul;59(7):1123-32. doi: 10.4187/respcare.02748. Epub 2013 Nov 12.
The primary aim of the disease management program (DMP) for patients with COPD is to improve health outcomes and thereby to reduce overall costs. Six years after its introduction in Germany, no consensus has yet been reached as to whether the DMP has been effective in reaching these goals. The objective of the study was an evaluation of the DMP for COPD in Bavaria using routinely collected subject medical records.
A longitudinal population-based study, comparing the total DMP population of up to 86,560 patients with a stable cohort of 17,549 subjects over a period of 5 years. The effect of subject dropout in the cohort is further estimated by means of inverse probability weighting.
The proportion of subjects in the total population who were prescribed and received treatment with oral corticosteroids declined at a constant rate of 1.0% per year (P < .001). The proportion of subjects who were given a prescription for theophylline decreased at a constant rate of 2.0% per year (P < .001). By 2012, 15.6% of the total population and 26% of the cohort had undergone self-management education. While the proportion of smokers in the total population remained constant because of the effect of newly enrolled subjects, the proportion of smokers decreased significantly even after dropout adjustment, from 29% to 21%. The occurrence of exacerbations decreased steadily at a rate of 0.9% (total population) or 0.7% (cohort) per year. While the occurrence of emergency hospital admissions decreased in the total population, an increase was observed within the cohort.
Summarizing all results leads to the suggestion that the German DMP for COPD has been effective in enhancing the quality of care in regard to an improved adherence to guidelines, pharmacotherapy, exacerbations, and self-management education. However, the DMP was not able to prevent an increase in emergency hospital admissions for the stable population in the cohort.
慢性阻塞性肺疾病(COPD)患者疾病管理项目(DMP)的主要目标是改善健康结局,从而降低总体成本。在德国引入该项目六年之后,对于DMP是否有效实现这些目标尚未达成共识。本研究的目的是利用常规收集的个体医疗记录对巴伐利亚州的COPD疾病管理项目进行评估。
一项基于人群的纵向研究,在5年时间内将多达86560名患者的DMP总人群与17549名受试者的稳定队列进行比较。通过逆概率加权进一步估计队列中个体退出的影响。
总体中接受口服糖皮质激素处方并接受治疗的受试者比例以每年1.0%的恒定速率下降(P <.001)。接受茶碱处方的受试者比例以每年2.0%的恒定速率下降(P <.001)。到2012年,总体人群中的15.6%和队列中的26%接受了自我管理教育。虽然由于新纳入受试者的影响,总体人群中吸烟者的比例保持不变,但即使在调整退出情况后,吸烟者的比例仍从29%显著下降至21%。急性加重的发生率以每年0.9%(总体人群)或0.7%(队列)的速率稳步下降。虽然总体人群中急诊住院的发生率有所下降,但在队列中却观察到有所增加。
综合所有结果表明,德国的COPD疾病管理项目在改善指南依从性、药物治疗、急性加重和自我管理教育方面有效地提高了护理质量。然而,该疾病管理项目未能阻止队列中稳定人群急诊住院人数的增加。