Department of Urology, Westmead Hospital University of Sydney, Sydney, Australia.
Prostate Int. 2013;1(1):42-5. doi: 10.12954/PI.12006. Epub 2013 Feb 4.
There is a paucity of information on the clinical efficacy and safety of the photoselective vaporization (PVP) of the prostate using the 180W lithium triborate (LBO) laser. We report on initial outcomes of PVP with the 180W laser, comparing the first 50 cases with the last 50 cases performed with the 120W LBO laser.
All cases performed by a single surgeon (HHW) have been prospectively maintained. The last 50 cases treated with the 120W LBO laser (December 2009 to August 2010) were compared with the first 50 cases treated with the 180W LBO (July 2010 to June 2011). Patient variables were recorded preoperatively and at 3 months postoperatively. Perioperative data was also recorded.
The 180W cases had a larger median transrectal ultrasound prostate volume (68 mL vs. 51 mL, P<0.05). For the 180W and 120W LBO lasers, total operating time was 64.2 and 72.5 minutes (not significant [NS] at P=0.22), lasering time 49.6 and 54.6 minutes (NS, P=0.30) and energy utilisation 477.6 kJ and 377.9 kJ (P<0.05) respectively. When compared per gram of prostate tissue lasered, the 180W is quicker at 0.67 min/g vs. 1.0 min/g for the 120W laser. Complications using the Clavien-Dindo classification included 5 grade 1 complications and 3 grade 3b (bladder neck contractures) with the 180W LBO laser. The 120 W LBO laser had 4 grade 1 complications and 1 grade 2.
There is little change in clinical outcomes with the transition from 120W to 180W LBO PVP with an already experienced PVP surgeon. The 180W LBO laser appears to have impacted upon patient selection with significantly increased prostate size and associated with increased energy utilisation. There appears to be a trend toward shorter laser times.
关于使用 180W 硼酸锂(LBO)激光进行前列腺光选择性汽化术(PVP)的临床疗效和安全性信息很少。我们报告了使用 180W 激光进行 PVP 的初步结果,将前 50 例与最后 50 例使用 120W LBO 激光进行的手术进行了比较。
所有由一位外科医生(HHW)进行的手术都进行了前瞻性维护。比较了最后 50 例使用 120W LBO 激光(2009 年 12 月至 2010 年 8 月)治疗的病例和前 50 例使用 180W LBO 激光(2010 年 7 月至 2011 年 6 月)治疗的病例。记录了患者术前和术后 3 个月的变量。还记录了围手术期数据。
180W 组的中位经直肠超声前列腺体积较大(68mL 比 51mL,P<0.05)。对于 180W 和 120W LBO 激光,总手术时间分别为 64.2 分钟和 72.5 分钟(P=0.22 时无统计学意义[NS]),激光时间分别为 49.6 分钟和 54.6 分钟(NS,P=0.30),能量利用率分别为 477.6kJ 和 377.9kJ(P<0.05)。按激光处理的前列腺组织每克进行比较,180W 激光处理速度更快,为 0.67 分钟/g,而 120W 激光为 1.0 分钟/g。使用 Clavien-Dindo 分类的并发症包括 5 级 1 例并发症和 3 级 3b 例(膀胱颈挛缩),使用 180W LBO 激光。120W LBO 激光有 4 级 1 例并发症和 1 级 2 例。
对于已有经验的 PVP 外科医生来说,从 120W 过渡到 180W LBO PVP,临床结果变化不大。180W LBO 激光似乎对患者选择产生了影响,前列腺体积明显增大,与能量利用率增加有关。激光时间似乎有缩短的趋势。