普通人群中终生焦虑症、情绪障碍和物质使用障碍的发病情况及时间顺序。
Onset and temporal sequencing of lifetime anxiety, mood and substance use disorders in the general population.
作者信息
Slade T, McEvoy P M, Chapman C, Grove R, Teesson M
机构信息
National Drug and Alcohol Research Centre University of New South Wales,Sydney,Australia.
Centre for Clinical Interventions, School of Psychology, University of Western Australia,Perth,Australia.
出版信息
Epidemiol Psychiatr Sci. 2015 Feb;24(1):45-53. doi: 10.1017/S2045796013000577. Epub 2013 Nov 15.
Abstract
Aims. To date, very few studies have examined the bi-directional associations between mood disorders (MDs), anxiety disorders (ADs) and substance use disorders (SUDs), simultaneously. The aims of the current study were to determine the rates and patterns of comorbidity of the common MDs, ADs and SUDs and describe the onset and temporal sequencing of these classes of disorder, by sex. Methods. Data came from the 2007 Australian National Survey of Mental Health and Wellbeing, a nationally representative household survey with 8841 (60% response rate) community residents aged 16-85. Results. Pre-existing mental disorders increase the risk of subsequent mental disorders in males and females regardless of the class of disorder. Pre-existing SUDs increase the risk of subsequent MDs and ADs differentially for males and females. Pre-existing MDs increase the risk of subsequent ADs differentially for males and females. Conclusions. Comorbidity remains a significant public health issue and current findings point to the potential need for sex-specific prevention and treatment responses.
摘要
目的。迄今为止，极少有研究同时考察情绪障碍（MDs）、焦虑障碍（ADs）和物质使用障碍（SUDs）之间的双向关联。本研究的目的是确定常见情绪障碍、焦虑障碍和物质使用障碍的共病率及模式，并按性别描述这些障碍类别的发病情况和时间顺序。方法。数据来自2007年澳大利亚全国心理健康与幸福调查，这是一项针对16 - 85岁社区居民的具有全国代表性的家庭调查，共8841人（回应率60%）。结果。无论障碍类别如何，既往存在的精神障碍都会增加男性和女性后续患精神障碍的风险。既往存在的物质使用障碍对男性和女性后续患情绪障碍和焦虑障碍的风险增加情况有所不同。既往存在的情绪障碍对男性和女性后续患焦虑障碍的风险增加情况也有所不同。结论。共病仍然是一个重大的公共卫生问题，当前研究结果表明可能需要针对不同性别的预防和治疗措施。
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