Kuz'min O B, Mikhaĭlenko P V, Kriukova R A
Farmakol Toksikol. 1986 Mar-Apr;49(2):21-4.
Indomethacin (3 mg/kg, orally for 5 days) prevented the increase of blood flow in the internal zone of the renal cortical layer but failed to interfere with the increase of diuresis and sodium secretion produced by furosemide (2 mg/kg, subcutaneously) in anesthetized rats. Contrykal (6000 ED, subcutaneously) failed to alter the character of the hemodynamic changes in the renal cortex but enhanced the diuretic and natriuretic effects of furosemide. In unanesthetized rats indomethacin prevented creatinine urine excretion but didn't attenuate the diuretic and natriuretic effects of furosemide.
吲哚美辛（3毫克/千克，口服5天）可防止麻醉大鼠肾皮质内层血流增加，但未能干扰速尿（2毫克/千克，皮下注射）所产生的利尿和钠分泌增加。抑肽酶（6000 ED，皮下注射）未能改变肾皮质血流动力学变化的特征，但增强了速尿的利尿和排钠作用。在未麻醉的大鼠中，吲哚美辛可防止肌酐尿排泄，但并未减弱速尿的利尿和排钠作用。
