Savina E A, Alekseev E I
Arkh Anat Gistol Embriol. 1980 Jan;78(1):62-8.
A comparative evaluation on some morphological indices of functional state of the posterior neurohypophysis was performed in rats subjected to weightlessness and artificial gravitation for 18.5 days on board the biosatellite "Cosmos-936". The data of the investigation were compared to those obtained on the test animals used for terrestial series of the experiment where all the factors of space flight, except weightlessness were imitated. As the analysis of morphological data demonstrated, a prolonged effect of weightlessness results in a considerable decrease in the number of the neurosecretory cumulative corpuscles (Herring's bodies), in decreasing volume of nuclei and size of pituicytes. A suggestion is made on decreasing basal level of functional activity of the hypothalamo-hypophyseal neurosecretory system under the conditions of weightlessness. Administration of artificial gravitation (lg) levels partly the changes produced by weightlessness and ensure a higher level of functioning in the neurosecretory system.
在“宇宙-936”生物卫星上,对经受18.5天失重和人工重力作用的大鼠垂体后叶功能状态的一些形态学指标进行了比较评估。将研究数据与在地面系列实验中使用的对照动物所获得的数据进行比较,在地面实验中模拟了除失重外的所有太空飞行因素。形态学数据分析表明,长期失重效应导致神经分泌累积小体(赫林体)数量显著减少,细胞核体积减小,垂体细胞大小减小。有人提出,在失重条件下,下丘脑-垂体神经分泌系统的基础功能活动水平会降低。施加人工重力(1g)可部分缓解失重产生的变化,并确保神经分泌系统具有更高的功能水平。