[在实验条件下（切除一叶肝脏或一个肾脏后），百炎净对白鼠胃黏膜状态的影响]

[Effect of Biseptol on the state of gastric mucosa in the white rat under experimental conditions (after excision of one lobe of the liver or one kidney)].

作者信息

Czerny K, Ciszewska-Popiołek B, Dowgird E

出版信息

Gegenbaurs Morphol Jahrb. 1986;132(2):291-7.

Abstract

The effect of Biseptol on the mucous membrane of the stomach of an unoperated white rat was analysed and also the effect after liver lobectomy or unilateral nephrectomy. There were performed histochemical reactions to mucopolysaccharides and nucleic acids as well as staining with hematoxyline ond eosine. After administration of Biseptol in a dose of 270 mg/kg b.w. for 7 consecutive d, increased secretion of mucous and inflammation in gastric mucous membrane was observed. No intensification of these symptoms was found after administration of Biseptol to operated animals. It may be supposed that hepatectomy and nephrectomy are not counterindications for the use of Biseptol.

摘要

分析了复方磺胺甲恶唑对未做手术的白鼠胃黏膜的影响，以及肝叶切除或单侧肾切除后的影响。进行了针对黏多糖和核酸的组织化学反应以及苏木精-伊红染色。以270毫克/千克体重的剂量连续7天给予复方磺胺甲恶唑后，观察到胃黏膜黏液分泌增加和炎症。给做手术的动物施用复方磺胺甲恶唑后，未发现这些症状加剧。可以推测，肝切除术和肾切除术并非使用复方磺胺甲恶唑的禁忌证。

相似文献

1

[Effect of Biseptol on the state of gastric mucosa in the white rat under experimental conditions (after excision of one lobe of the liver or one kidney)].[在实验条件下（切除一叶肝脏或一个肾脏后），百炎净对白鼠胃黏膜状态的影响]

Gegenbaurs Morphol Jahrb. 1986;132(2):291-7.

2

[Histochemical and electrophoretic determination of a selected element of the rat myocardium metabolism as exemplified by lactate dehydrogenase (LDH/E.C.1.1.1.27/) following administration of the preparation Biseptol 480 (co-trimoxazole)].[以服用必思添480（复方新诺明）后乳酸脱氢酶（LDH/E.C.1.1.1.27/）为例，对大鼠心肌代谢选定元素进行组织化学和电泳测定]

Gegenbaurs Morphol Jahrb. 1985;131(3):337-46.

3

[Histochemical and electrophoretic studies of lactate dehydrogenase (LDH/E.C. 1.1.1.27/) activity in the rat liver following the administration of Biseptol 480 (co-trimoxazole)].[服用百炎净480（复方新诺明）后大鼠肝脏中乳酸脱氢酶（LDH/E.C. 1.1.1.27/）活性的组织化学和电泳研究]

Gegenbaurs Morphol Jahrb. 1984;130(6):761-7.

4

The effect of Biseptol 480 on the spleen and the view of rat peripheral blood after surgical removal of the liver lobe.复方磺胺甲恶唑480对大鼠肝叶切除术后脾脏及外周血的影响。

Patol Pol. 1984 Apr-Jun;35(2):223-30.

5

[Behavior of selected oxidoreductases in histochemical and electro- phoretic studies of the rat kidney after administration of Biseptol 480 (co-trimoxazole)].[服用必思添480（复方新诺明）后大鼠肾脏组织化学和电泳研究中所选氧化还原酶的行为]

Gegenbaurs Morphol Jahrb. 1985;131(4):525-35.

6

Effect of Biseptol 480 on the spleen and on the peripheral blood leucocyte count of nephrectomized rats.复方新诺明480对肾切除大鼠脾脏及外周血白细胞计数的影响。

Folia Morphol (Praha). 1985;33(2):135-8.

7

The influence of Biseptol 480 on histochemical reactions in the testicle of the rat after surgical removal of a kidney or a liver lobe.必嗽平480对大鼠肾或肝叶切除术后睾丸组织化学反应的影响

Ann Univ Mariae Curie Sklodowska Med. 1985;40:113-8.

8

[Effect of biseptol on the adrenal cortex of the white rat in postoperative shock].[复方新诺明对大白鼠术后休克肾上腺皮质的影响]

Gegenbaurs Morphol Jahrb. 1986;132(1):111-27.

9

[Effect of Biseptol 480 on the cells of the exocrine part of the pancreas after surgical removal of the hepatic lobe].[肝叶切除术后百炎净480对胰腺外分泌部细胞的影响]

Ann Univ Mariae Curie Sklodowska Med. 1983;38:179-85.

10

[The effect of biseptol and sodium salicylate administration on the concentration of serotonin and histamine and mono- and diamine oxidase activities in rat placenta].[服用复方磺胺甲恶唑和水杨酸钠对大鼠胎盘血清素、组胺浓度及单胺氧化酶和二胺氧化酶活性的影响]

Probl Med Wieku Rozwoj. 1982;11:143-7.

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