Paciftc Analytical, Inc., 6349 Paseo Del Lago, 92009, Carlsbad, CA.
J Am Soc Mass Spectrom. 1992 Jul;3(5):558-62. doi: 10.1016/1044-0305(92)85033-G.
The use of mass chromatogram peak centroids has been investigated as a means of deconvoluting the spectra of overlapping gas chromatography/mass spectrometry components. The peak centroids have been calculated with a precision of 0.04 scans (sd). This proved sufficient to allow deconvolution of the mass spectra belonging to two chemical components which were eluted 0.48 scans apart. For a more complex chromatography peak, it was possible to deconvolute the spectra of six components which were eluted within a 9 scan window. All the spectra produced by using this deconvolution mechanism agreed well with National Institute of Standards and Technology database spectra.
已经研究了使用质量色谱峰质心作为解析重叠气相色谱/质谱成分谱图的方法。峰质心的计算精度为 0.04 扫描（标准差）。这足以允许对相隔 0.48 扫描洗脱的两种化学组分的质谱进行反卷积。对于更复杂的色谱峰，可以解析在 9 扫描窗口内洗脱的六个组分的光谱。使用这种反卷积机制生成的所有光谱都与美国国家标准与技术研究院数据库的光谱吻合良好。
