Wang Liang, Wang Ke-Sheng
Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, P.O. Box 70259, Lamb Hall, Johnson City, TN 37614-1700, USA.
Psychiatry J. 2013;2013:979623. doi: 10.1155/2013/979623. Epub 2013 Mar 17.
Few studies have examined the risk factors of serious psychological distress (SPD) and behavioral factors for heart disease separately stratified as young (18-44 years), middle aged (45-64 years), and elderly (65 years or older). A total of 3,540 adults with heart disease and 37,703 controls were selected from the 2005 California Health Interview Survey. Data were weighted to be representative and adjusted for potential undercoverage and nonresponse biases. Multiple logistic regression models were used to estimate the associations of the factors with heart disease at different ages. The prevalence of SPD was 8% in cases and 4% in controls, respectively. For young adults, SPD and higher federal poverty level (FPL) were associated with an increased risk of heart disease while for middle-aged adults, SPD, past smoking, lack of physical activity, obesity, male, and unemployment were associated with an increased risk of heart disease. In addition, SPD, past smoking, lack of physical activity, obesity, male, unemployment, White, and lower FPL were associated with an increased risk of heart disease in elderly. Our findings indicate that risk factors for heart disease vary across all ages. Intervention strategies that target risk reduction of heart disease may be tailored accordingly.
很少有研究分别按年轻人（18 - 44岁）、中年人（45 - 64岁）和老年人（65岁及以上）分层，来考察严重心理困扰（SPD）的风险因素以及心脏病的行为因素。从2005年加利福尼亚健康访谈调查中选取了总共3540名患有心脏病的成年人和37703名对照者。对数据进行加权以使其具有代表性，并针对潜在的覆盖不足和无应答偏差进行调整。使用多重逻辑回归模型来估计不同年龄段这些因素与心脏病之间的关联。病例组中SPD的患病率分别为8%，对照组为4%。对于年轻人，SPD和较高的联邦贫困水平（FPL）与心脏病风险增加相关；而对于中年人，SPD、既往吸烟、缺乏体育活动、肥胖、男性和失业与心脏病风险增加相关。此外，SPD、既往吸烟、缺乏体育活动、肥胖、男性、失业、白人以及较低的FPL与老年人心脏病风险增加相关。我们的研究结果表明，心脏病的风险因素在所有年龄段各不相同。针对降低心脏病风险的干预策略可能需要相应地进行调整。
