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选择与小鼠身体成分相关的成分:直接反应。

Selection for components related to body composition in mice: direct responses.

机构信息

Animal Science Department, North Carolina State University, Box 7621, 27695-7621, Raleigh, NC, USA.

出版信息

Theor Appl Genet. 1987 Oct;74(6):793-801. doi: 10.1007/BF00247559.

DOI:10.1007/BF00247559
PMID:24240342
Abstract

Replicated within full-sib family single-trait selection was conducted for 10 generations in mice for (1) high or low 12-week epididymal fat pad percentage (100 x epididymal fat pad weight/body weight) or (2) high or low 12-week hind carcass percentage (100 x hind carcass weight/body weight). Pooled realized heritabilities based on high, low and divergent selection were 0.66±0.09, 0.65±0.13 and 0.66±0.05 for epididymal fat pad percentage and 0.48±0.08, 0.33±0.08 and 0.40±0.04 for hind carcass percentage. The pooled realized genetic correlation (rG R) between epididymal fat pad percentage and hind carcass percentage based on divergence was -0.67±0.04. Other estimates of (rG R) were: epididymal fat pad percentage with body weight (0.57±0.05); epididymal fat pad percentage with epididymal fat pad weight (1.17±0.05); hind carcass percentage with body weight (-0.61±0.09); hind carcass percentage with hind carcass weight (-0.05±0.11). Indirect measures of fat and lean tissue percentages were highly heritable, and (rG R) between them would be desirable from the standpoint of analogous types of traits in livestock. In the same context, undesirable (rG R)'s were found between epididymal fat pad percentage and body weight and between hind carcass percentage and body weight.

摘要

在小鼠中进行了全同胞家系单性状选择,选择的性状为:(1)12 周附睾脂肪垫百分比(100x 附睾脂肪垫重量/体重)高或低,或(2)12 周后腿体百分比(100x 后腿体重量/体重)高或低。基于高、低和分歧选择的综合现实遗传力分别为附睾脂肪垫百分比的 0.66±0.09、0.65±0.13 和 0.66±0.05,后腿体百分比的 0.48±0.08、0.33±0.08 和 0.40±0.04。基于分歧的附睾脂肪垫百分比和后腿体百分比的综合现实遗传相关系数(rG R)为-0.67±0.04。其他 rG R 的估计值为:附睾脂肪垫百分比与体重(0.57±0.05);附睾脂肪垫百分比与附睾脂肪垫重量(1.17±0.05);后腿体百分比与体重(-0.61±0.09);后腿体百分比与后腿体重量(-0.05±0.11)。脂肪和瘦肉组织百分比的间接测量值具有高度遗传力,从家畜中类似类型的性状的角度来看,它们之间的 rG R 是理想的。在相同的背景下,发现附睾脂肪垫百分比与体重之间以及后腿体百分比与体重之间存在不理想的 rG R。

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引用本文的文献

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Rabbit Lines Divergently Selected for Total Body Fat Content: Correlated Responses on Growth Performance and Carcass Traits.针对全身脂肪含量进行 divergent 选择的兔子品系:生长性能和胴体性状的相关反应。 注:“divergent”可能是“趋异的”意思,但不太确定这个词在该专业语境下准确含义,所以直接保留原文。 你可根据实际情况进一步确认和调整。
Animals (Basel). 2020 Oct 6;10(10):1815. doi: 10.3390/ani10101815.
2
Correlated responses in development and distribution of fat depots in mice selected for body composition traits.选择体成分特征的小鼠脂肪沉积发育和分布的相关反应。
Theor Appl Genet. 1989 Aug;78(2):217-23. doi: 10.1007/BF00288802.
3
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本文引用的文献

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Rate, composition and efficiency of growth in mice selected for large and small body weight.选择大、小体重的小鼠的生长速度、组成和效率。
Theor Appl Genet. 1969 Jan;39(7):306-14. doi: 10.1007/BF00281911.
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Theor Appl Genet. 1992 May;83(8):973-80. doi: 10.1007/BF00232959.
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Variation in within-bone stiffness measured by nanoindentation in mice bred for high levels of voluntary wheel running.通过对高运动量自发转轮育成的小鼠进行骨内硬度的纳米压痕测量发现其存在差异。
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Genet Res. 2006 Feb;87(1):45-60. doi: 10.1017/S0016672306007944.
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5
The developmental characteristics of two strains of chickens selected for differences in mature abdominal fat pad size.两株因成熟腹部脂肪垫大小不同而被选育的鸡的发育特征。
Growth. 1982 Summer;46(2):171-81.
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Effects of selection on growth, body composition and food intake in mice. I. Responses in selected traits.选择对小鼠生长、身体组成和食物摄入量的影响。I. 所选性状的反应
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The correlation between feed efficiency and rate of gain, a ratio and its denominator.饲料效率与生长速度之间的相关性,一个比率及其分母。
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