Khan Fahmi Yousef, Abukhattab Mohammed, Anand Deshmukh
Department of Medicine, Hamad General Hospital, Doha, Qatar.
J Neurosci Rural Pract. 2013 Jul;4(3):349-51. doi: 10.4103/0976-3147.118800.
We report four cases of nosocomial E. coli meningitis, in male patients with accidental and neurosurgical trauma. The interval between accidents/neurosurgical procedures and the onset of meningitis was 2-15 days (mean 6.25 days). The most consistent clinical features were fever and deterioration of consciousness level. Emergence of extended spectrum beta lactamase E. coli strains had been observed in two (50%) of our cases and the mean duration of antimicrobial treatment was 16.5 days (range: 6-24 days). Two of the four patients (50%) died in the hospital.
我们报告了4例医院获得性大肠杆菌脑膜炎病例，患者均为男性，有意外创伤和神经外科手术史。事故/神经外科手术后至脑膜炎发病的间隔时间为2至15天（平均6.25天）。最常见的临床特征是发热和意识水平下降。在我们的2例（50%）病例中观察到产超广谱β-内酰胺酶的大肠杆菌菌株，抗菌治疗的平均持续时间为16.5天（范围：6至24天）。4例患者中有2例（50%）在医院死亡。
